Therapeutic drug monitoring by LC-MS-MS with special focus on anti-infective drugs

Analytical and Bioanalytical Chemistry
Daniel M Müller, Katharina M Rentsch

Abstract

Liquid chromatography coupled to mass spectrometry nowadays plays an important role in the field of therapeutic drug monitoring (TDM), especially of new compounds for which no immunoassays are available. This paper reviews LC-MS(-MS) methods published recently for anti-infective drugs: antiretroviral drugs, other antiviral drugs, antibacterial drugs, antihelmintic drugs, antimalarial drugs, and other antiprotozoal drugs. An overview of the different methods is given, with special focus on selection of the internal standard and validation procedures.

References

Sep 14, 2000·Journal of Chromatography. B, Biomedical Sciences and Applications·N Lindegårdh, Y Bergqvist
Apr 25, 2001·Journal of Chromatography. B, Biomedical Sciences and Applications·R A MirghaniL L Gustafsson
Aug 28, 2001·Biopharmaceutics & Drug Disposition·J A Kolawole, A Mustapha
Oct 24, 2001·International Journal of Antimicrobial Agents·K BornerH Lode
Feb 1, 2002·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·L Aït MoussaB Hüe
Feb 7, 2002·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·M Y Khuhawar, F M A Rind
Feb 28, 2002·Journal of Pharmaceutical and Biomedical Analysis·Wibool RidtitidMethi Sunbhanich
Jun 22, 2002·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·C SouppartF Richard
Oct 29, 2002·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Chia-Hsien FengSu-Hwei Chen
Nov 1, 2002·Journal of Pharmaceutical and Biomedical Analysis·A MirfazaelianM R Rouini
Nov 27, 2002·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Pierina Sueli BonatoOsvaldo Massaiti Takayanagui
Dec 25, 2002·Antimicrobial Agents and Chemotherapy·Sylvie LarratClaude Souvignet
Jun 12, 2003·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Marcos FernándezCarlos von Plessing
Aug 9, 2003·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·S SentenacG Aymard
Sep 5, 2003·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Brian G KeevilDonald P Cooper
Sep 6, 2003·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Asa JanssonRajaa A Mirghani
Dec 9, 2003·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·E N GitauG O Kokwaro
Apr 3, 2004·Journal of Chromatography. a·Ignacio CallejaMaría Carmen Dios-Viéitez
Apr 6, 2004·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Yifei LiuLi-Tain Yeh
Sep 25, 2004·Antimicrobial Agents and Chemotherapy·Yoichi InoueYukinao Kohda
Nov 10, 2004·Journal of Pharmaceutical and Biomedical Analysis·Warunee HanpitakpongKesara Na-Bangchang
Jan 25, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Himanshu NaikLawrence Fleckenstein
Jan 25, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Gh BahramiA Kiani
Mar 31, 2005·Journal of Pharmaceutical and Biomedical Analysis·Ticiano Gomes do NascimentoRui Oliveira Macêdo
May 24, 2005·Journal of Pharmaceutical and Biomedical Analysis·Victoria F SamanidouIoannis N Papadoyannis
Jun 1, 2005·Journal of Pharmaceutical and Biomedical Analysis·Cyriaque SaganIvan Brumpt
Nov 5, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Tom DelahuntyCourtney V Fletcher
Nov 18, 2005·Biomedical Chromatography : BMC·Lauren M BoakCraig R Rayner
Feb 4, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Yifei LiuChin-chung Lin
Mar 30, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Antonio D'AvolioGiovanni Di Perri
Jun 13, 2006·Journal of Pharmaceutical and Biomedical Analysis·Deqing SunRuichen Guo
Jul 4, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Geetha RamachandranSoumya Swaminathan

❮ Previous
Next ❯

Citations

Dec 19, 2012·Journal of Pharmaceutical and Biomedical Analysis·Syeda A B ShahDeclan P Naughton
May 11, 2016·Clinical Biochemistry·Maria Shipkova, Dobrin Svinarov
Sep 11, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ibrahim A DarwishRashed N Herqash
May 14, 2021·Critical Reviews in Analytical Chemistry·Ozge SelcukBengi Uslu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.