Therapeutic effect of microneedling and autologous platelet-rich plasma in the treatment of atrophic scars: A randomized study

Journal of Cosmetic Dermatology
Zeinab A IbrahimOla A Shora

Abstract

New treatments and techniques were being added over the last few years to treat atrophic scars with variable results and adverse effects. The aim of this study was to evaluate and compare the therapeutic efficacy and safety of microneedling, autologous platelet-rich plasma, and combination of both procedures in the treatment of atrophic scars. This study included 90 patients with atrophic scars and were classified randomly into three groups: I: 28 patients treated with microneedling, one session every 4 weeks; II: 34 patients treated with intradermal injection of platelet-rich plasma, one session every 2 weeks; and III: 28 patients treated with alternative sessions of each microneedling and platelet-rich plasma, 2 weeks between each session, for a maximum of six sessions. There was a statistically significant improvement in the appearance of atrophic scars, with reduction in the scores associated with the clinical evaluation scale for atrophic scarring in all groups, but the improvement was more obvious in group III. Although a single treatment may give good results, combination between skin needling and platelet-rich plasma is more effective, safe with less number of sessions in all types of atrophic scars.

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Citations

May 10, 2019·Journal of Cosmetic Dermatology·Elizabeth SchoenbergNazanin Saedi
Sep 12, 2019·Aesthetic Plastic Surgery·Tyng-Shiuan HsiehChiehfeng Chen
Nov 13, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Amelia K Hausauer, Shannon Humphrey
Jul 30, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Nisma MujahidNeelam A Vashi
Nov 27, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Amelia K Hausauer, Shannon Humphrey
Jul 10, 2020·The Journal of Dermatological Treatment·Zainab A IbrahimDareen A Mohammed
Dec 15, 2018·Journal of Cosmetic Dermatology·Amr N SaadawiWalaa El-Sayed
Jul 1, 2020·Journal of Cosmetic Dermatology·Alessia VillaniGabriella Fabbrocini
Mar 1, 2019·Therapeutic Advances in Chronic Disease·Lucía Gato-CalvoElena F Burguera
Aug 18, 2020·Clinical, Cosmetic and Investigational Dermatology·Yanyan DengGaoyun Yang
Dec 31, 2020·Clinical, Cosmetic and Investigational Dermatology·Margit L W Juhasz, Joel L Cohen
Jul 11, 2021·Indian Journal of Dermatology, Venereology and Leprology·K MuthuprabakaranPankaj Shukla

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