Therapeutic Effects of Bilateral Anodal Transcranial Direct Current Stimulation on Prefrontal and Motor Cortical Areas in Children with Autism Spectrum Disorders: A Pilot Study.

Autism Research : Official Journal of the International Society for Autism Research
Hikmat HadoushMaha Alafeef

Abstract

Dysfunctional frontal cortical areas associated with clinical features are observed in children with autism spectrum disorder (ASD). This study attempted to identify any potential therapeutic effects of bilateral anodal transcranial direct current stimulation (tDCS) applied over the left and right prefrontal and motor areas on the clinical characteristics of children with ASD. Fifty children with confirmed ASD medical diagnoses were divided equally and randomly into a tDCS treatment group and a control group. The tDCS treatment group underwent 10 sessions (20-min durations, five per week) of bilateral anodal tDCS stimulation applied simultaneously over the left and right prefrontal and motor areas, whereas the control group underwent the same procedures but with the use of sham tDCS stimulation. Total scores and sub-scores of autism treatment evaluation checklist (ATEC) (language and communication; sociability; sensory awareness; and behavioral, health, and physical conditions) were measured before and after the tDCS treatment sessions of both groups. There were significant decreases in total ATEC scores (P = 0.014), sociability sub-scores (P = 0.021), and behavioral, health, and physical condition sub-scores (P = 0.011) in the...Continue Reading

References

Sep 5, 2001·Nature Reviews. Neuroscience·G RizzolattiV Gallese
Apr 19, 2003·Proceedings of the National Academy of Sciences of the United States of America·Laurie CarrGian Luigi Lenzi
Mar 17, 2004·Controlled Clinical Trials·Heejung BangClarence E Davis
Mar 19, 2005·Brain : a Journal of Neurology·Dana SamsonGlyn W Humphreys
Apr 13, 2006·Journal of Autism and Developmental Disorders·Eva M JansiewiczStewart H Mostofsky
Jun 10, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Pedro Cavaleiro MirandaMark Hallett
Jul 27, 2006·Journal of Autism and Developmental Disorders·Beth ProvostSandra Heimerl
Nov 23, 2006·Nature Reviews. Neuroscience·Marco Iacoboni, Mirella Dapretto
Sep 7, 2007·Journal of Autism and Developmental Disorders·Sally OzonoffSally J Rogers
Sep 18, 2009·Experimental Brain Research·Giacomo Rizzolatti, Maddalena Fabbri-Destro
Apr 20, 2010·Gait & Posture·Kimberly A FournierChris J Hass
Aug 17, 2010·Brain & Development·Gianluca EspositoFilippo Muratori
Jul 4, 2012·Neuropharmacology·Asli Demirtas-TatlidedeAlvaro Pascual-Leone
Jul 31, 2012·Neuroscience and Biobehavioral Reviews·Suzanne CoghlanDavid J Nutt
Aug 2, 2013·JAMA Psychiatry·Ryan C CardinaleRalph-Axel Müller
Aug 6, 2013·Journal of Mental Health Research in Intellectual Disabilities·David A GeierMark R Geier
Dec 18, 2013·Biological Psychiatry·Giordano D'UrsoCarmela Bravaccio
Mar 29, 2014·ELife·Charlotte J StaggHeidi Johansen-Berg
Dec 23, 2014·Behavioural Neurology·Anuwat AmatachayaParadee Auvichayapat
Jan 28, 2015·NeuroImage·Roozbeh BehroozmandJeremy D W Greenlee
Mar 12, 2015·Proceedings of the National Academy of Sciences of the United States of America·Douglass GodwinRené Marois
Mar 25, 2015·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Giordano D'UrsoCarmela Bravaccio
Sep 10, 2016·Autism Research : Official Journal of the International Society for Autism Research·Nicolaas A J PutsRichard A E Edden
Feb 22, 2017·Neuromodulation : Journal of the International Neuromodulation Society·Cristina RussoFelipe Fregni
Aug 12, 2018·Progress in Brain Research·Dorothea L Floris, Henrietta Howells

❮ Previous
Next ❯

Citations

Mar 29, 2021·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Sara García-GonzálezJosep Antoni Ramos-Quiroga
May 22, 2021·Autism Research : Official Journal of the International Society for Autism Research·Mohammad Ali SalehinejadVahid Nejati
Aug 12, 2021·Journal of Translational Medicine·Jin CaoJian Kong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autism: Motor Learning

A common feature of autism spectrum disorder (ASD) is the impairment of motor control and learning, consistent with perturbation in cerebellar function. Find the latest research on ASD and motor learning here.

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.