Aug 27, 2013

Therapeutic effects of Shenfu Injection on post-cardiac arrest syndrome

Chinese Journal of Integrative Medicine
Zhi-Jun Guo, Chun-Sheng Li

Abstract

Survival rates after cardiac arrest have not changed substantially over the past 5 decades. Postcardiac arrest (CA) syndrome (PCAS) is the primary reason for the high mortality rate after successful restoration of spontaneous circulation (ROSC). Intravenous administration of Shenfu Injection (, SFI) may attenuate post-CA myocardial dysfunction and cerebral injury, inhibit systemic ischemia/reperfusion responses, and treat underlying diseases. In this article, we reviewed the therapeutic effects of SFI in PCAS. SFI might be useful in the treatment of PCAS, incorporating the multi-link and multi-target advantages of Chinese medicine into PCAS management. Further experimental and clinical research to verify the therapeutic effects of SFI in PCAS is required.

Mentioned in this Paper

Ischemia
Brain
Myocardial Dysfunction
Cardiomyopathies
Medicine, Chinese
Cerebral Hemisphere Structure (Body Structure)
Cardiotonic Agents
Physiological Reperfusion
Neuroprotective Effect
Shen-Fu

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