PMID: 8937834Oct 1, 1996Paper

Therapeutic horizons for amyotrophic lateral sclerosis

Current Opinion in Neurobiology
J D Rothstein

Abstract

Recent theories on the pathogenesis of motor neuron disease and research on motor neuron injury have resulted in new putative therapies, which include treatment with various neurotrophic factors, antioxidants and anti-excitotoxicity agents. Clinical and preclinical studies have now provided the first agents that reproducibly alter the course of amyotrophic lateral sclerosis.

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Citations

May 5, 2005·Experimental Neurology·Roger S ChungJames C Vickers
Dec 16, 1998·Journal of the Neurological Sciences·L P Rowland
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