PMID: 8081644Jun 1, 1994Paper

Therapeutic interaction of lamotrigine and sodium valproate in intractable myoclonic epilepsy

Seizure : the Journal of the British Epilepsy Association
C D Ferrie, C P Panayiotopoulos

Abstract

The clinical and EEG features of a 13-year-old girl with an unusual refractory myoclonic epilepsy is presented. Control was achieved only when lamotrigine was combined with sodium valproate. This may represent a specific pharmacodynamic interaction between these drugs with implications for therapy in the generalized epilepsies.

References

May 23, 1992·Lancet·P L Timmings, A Richens
Nov 14, 1992·Lancet·J StewartE H Reynolds
Feb 13, 1993·Lancet·C P PanayiotopoulosR O Robinson
May 8, 1993·Lancet·F PisaniA Richens

❮ Previous
Next ❯

Citations

Aug 4, 2009·European Journal of Drug Metabolism and Pharmacokinetics·Mladena LalicMomir Mikov
Jan 1, 1995·Pharmacology & Therapeutics·G E Mawer, B J Pleuvry
Aug 15, 2000·Epilepsy Research·E PeruccaT Tomson
Jun 12, 2003·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Antonio CuadradoJuan A Armijo
Mar 1, 1996·Seizure : the Journal of the British Epilepsy Association·G J SchapelW B Dollman
Jun 1, 1996·Seizure : the Journal of the British Epilepsy Association·N Buchanan
Aug 25, 2001·Epilepsia·E Perucca
Apr 16, 2002·Epilepsia·Philip N PatsalosClementina M van Rijn
Dec 5, 2008·Epilepsia·Jeremy J MoellerR Mark Sadler
Sep 1, 1996·Archives of Disease in Childhood·R E Appleton
Jul 14, 2012·Drug, Healthcare and Patient Safety·Amy Z CrepeauElaine C Wirrell
Jan 1, 1997·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·C D Ferrie, J H Livingston
Mar 16, 2001·Expert Opinion on Pharmacotherapy·P H McCabe
Sep 25, 2008·Arquivos de neuro-psiquiatria·Karen P GrisottoLúcia H C Santos
Jul 26, 2010·Pharmaceuticals·Jong Woo Lee, Barbara Dworetzky
Mar 1, 1995·Acta Neurologica Scandinavica·C D FerrieC P Panayiotopoulos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.