Therapeutic Options for Unscheduled Bleeding Associated with Long-Acting Reversible Contraception

Obstetrics and Gynecology Clinics of North America
EmmaKate Friedlander, Bliss Kaneshiro

Abstract

Long-acting reversible contraception (LARC) is the most effective form of reversible contraception. Although most women are satisfied with LARC methods, unscheduled bleeding and spotting are common reasons for method dissatisfaction and discontinuation. This systematic analysis of the current literature delineates treatment options for unscheduled bleeding related to LARC use. Although consistent results are lacking, all devices seem to have the best response to nonsteroidal antiinflammatory drugs for 5 to 7 days or the antifibrinolytic agent tranexamic acid. Additional studies are necessary to identify improved treatment interventions for unscheduled bleeding with LARC use.

References

Jul 1, 1987·Contraception·M Toppozada
Mar 1, 1986·British Journal of Obstetrics and Gynaecology·L Mäkäräinen, O Ylikorkala
Feb 14, 2006·Contraception·Vorapong PhupongSurasak Taneepanichskul
Sep 29, 2007·Contraception·Caroline MoreauJames Trussell
Aug 9, 2008·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Diana MansourIan S Fraser
Mar 13, 2010·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Suman LalNutan Agarwal
Apr 12, 2011·Contraception·Petra M CaseyJessica E Bury
Nov 8, 2011·American Journal of Obstetrics and Gynecology·Tessa MaddenJeffrey F Peipert

Citations

Sep 24, 2019·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Andrea M PetersonAngela R Dempsey
Jul 22, 2020·Current Opinion in Pediatrics·Alexandra J EdwardsSarah Pitts

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