Therapeutic plasmapheresis for hypertriglyceridemia-associated acute pancreatitis: case series and review of the literature

Therapeutic Advances in Endocrinology and Metabolism
Kiran JoglekarAmik Sodhi

Abstract

Severe hypertriglyceridemia (HTG) is the third leading cause of acute pancreatitis (AP) in the United States. The current standard of care includes management of HTG using pharmacological therapy. More recently, plasmapheresis has been proposed as a therapeutic tool for decreasing triglyceride (TG) levels, especially in critically ill patients. Few studies are available to ascertain overall benefits of plasmapheresis over traditional management. To analyze the outcomes of patients treated with plasmapheresis for severe HTG-associated pancreatitis. We conducted a retrospective chart review of three patients with severe HTG- associated (TGs greater than 1000 mg/dl; 11.29 mmol/l) AP at the Methodist University Hospital. All the patients underwent plasmapheresis as part of their treatment. The average TG level before plasmapheresis was 3532 mg/dl (range: 2524-4562 mg/dl; 39.9 mmol/l; range: 28.5-51.6 mmol/l). All patients made a full recovery, with a significant improvement in TG levels after plasmapheresis. The mean number of sessions was 1.3 (range 1-2), and mean TG level after plasmapheresis was 1051 mg/dl (range: 509-1771 mg/dl; 11.9 mmol/l; range: 5.8-20 mmol/l). After the first session, the average reduction of TG level was 2...Continue Reading

References

Jul 20, 2004·World Journal of Gastroenterology : WJG·Jui-Hao ChenChao-Sheng Liao
May 4, 2006·Digestive Diseases and Sciences·Hakan AlagözlüSelahattin Unal
Aug 31, 2006·Digestion·A V KyriakidisS Lambropoulos
Jun 7, 2007·World Journal of Gastroenterology : WJG·Pankaj JainAmit Mathur
Jun 27, 2008·Pancreas·Célia Lloret LinaresEric Bruckert
Jun 24, 2010·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Seon Young ParkMin Young Chung
Jan 21, 2012·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Jennifer D Twilla, Jimmie Mancell
Apr 17, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Shreyas SaligramDhiraj Yadav
Sep 11, 2012·The Journal of Clinical Endocrinology and Metabolism·Lars BerglundUNKNOWN Endocrine society
Apr 5, 2013·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Claudia StefanuttiClaudia Morozzi
Apr 11, 2013·Anaesthesiology Intensive Therapy·Wojciech SzczeklikMaria Kózka
Sep 10, 2013·European Journal of Internal Medicine·A Ramírez-BuenoP Valdivielso
Oct 2, 2014·European Journal of Internal Medicine·Pedro ValdivielsoNils Ewald
Mar 25, 2015·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Benjamin ClickDhiraj Yadav
Sep 10, 2015·Journal of Clinical Lipidology·Isabel Galán CarrilloFernando Anaya
Sep 24, 2015·International Journal of Surgery·Annika CharlesworthMartin A Crook
Mar 8, 2016·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Chakri GavvaJames Burner
Mar 26, 2016·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Rosalie A CarrNicholas J Zyromski
May 22, 2016·Journal of Clinical Lipidology·Weerapan KhovidhunkitWanee Plengpanich
Jun 21, 2016·Journal of Clinical Gastroenterology·Kishore VipperlaDhiraj Yadav
Oct 7, 2016·Postgraduate Medicine·Pamela A Kushner, Michael E Cobble

❮ Previous
Next ❯

Citations

Jul 29, 2017·Journal of Clinical Apheresis·Aaron Shmookler, Stephen Smith
Dec 15, 2017·Therapeutic Advances in Endocrinology and Metabolism·Shaikh Ahmed Muntajib WassayIbrahim Mansoor
Oct 12, 2018·Journal of Pediatric Endocrinology & Metabolism : JPEM·Engin KoseNur Arslan
Feb 8, 2019·Current Opinion in Critical Care·Elisabeth De WaeleHerbert D Spapen
Feb 15, 2020·Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners·Arundati RaoIbrahim Elali
Sep 29, 2017·Current Opinion in Lipidology·Anthony C Keech, Alicia J Jenkins
Mar 20, 2020·ANZ Journal of Surgery·Renee TaboneTerence C Chua
May 2, 2019·Clinical Journal of Gastroenterology·Giovanna Del Vecchio BlancoOmero Alessandro Paoluzi
May 12, 2019·Journal of Internal Medicine·Amanda J BerberichRobert A Hegele
May 15, 2020·Journal of Investigative Medicine High Impact Case Reports·Lindsey C ShipleyChad M Burski
Aug 28, 2020·Frontiers in Endocrinology·Debapriya Basu, Karin E Bornfeldt
Oct 14, 2020·BMJ : British Medical Journal·Vinaya Simha
Jan 5, 2021·Respiratory Medicine Case Reports·Hamel PatelHadi Hatoum

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Internal Medicine
A Ramírez-BuenoP Valdivielso
Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine
Prashant NasaKandy Koul
Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
A V KyriakidisG Antsaklis
© 2022 Meta ULC. All rights reserved