Therapeutic potential of histamine H3 receptor agonists and antagonists

Trends in Pharmacological Sciences
Rob LeursH Timmerman

Abstract

The histamine H3 receptor was discovered 15 years ago, and many potent and selective H3 receptor agonists and antagonists have since been developed. Currently, much attention is being focused on the therapeutic potential of H3 receptor ligands. In this review, Rob Leurs, Patrizio Blandina, Clark Tedford and Henk Timmerman describe the available H3 receptor agonists and antagonists and their effects in a variety of pharmacological models in vitro and in vivo. The possible therapeutic applications of the various compounds are discussed.

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Citations

Jan 27, 2004·Bioorganic & Medicinal Chemistry Letters·Marlon CowartArthur A Hancock
Dec 9, 2003·European Journal of Pharmacology·Lisan ZhangHenk Timmerman
Dec 9, 2003·European Journal of Pharmacology·Betty Bei YaoArthur A Hancock
Mar 23, 2004·European Journal of Pharmacology·Arthur A HancockBetty B Yao
Jun 2, 2005·Il Farmaco·Paolo ToscoAlberto Gasco
Nov 6, 2002·Clinica Chimica Acta; International Journal of Clinical Chemistry·Guo-Lin ChenHong-Hao Zhou
Jan 5, 2002·European Journal of Pharmacology·L Ireland-DennyA A Hancock
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Jun 24, 2003·European Journal of Pharmacology·Mohammad Reza ZarrindastMousa Sahebgharani
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Jul 13, 2002·Bioorganic & Medicinal Chemistry Letters·Ramin FaghihYoussef L Bennani
Aug 17, 2002·Bioorganic & Medicinal Chemistry Letters·Pauline TingRobert West
Oct 10, 2002·Bioorganic & Medicinal Chemistry Letters·Ramin FaghihArthur A Hancock
Oct 10, 2002·Bioorganic & Medicinal Chemistry Letters·Anil VasudevanArthur A Hancock
Oct 24, 2002·Bioorganic & Medicinal Chemistry Letters·Chandra ShahNicholas I Carruthers
Mar 27, 2003·Bioorganic & Medicinal Chemistry Letters·Ramin FaghihArthur A Hancock
May 6, 2003·Bioorganic & Medicinal Chemistry Letters·Wenying ChaiTodd K Jones
Jun 5, 2003·Bioorganic & Medicinal Chemistry Letters·Robert AslanianJohn A Hey

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