Therapeutic potential of Terminalia arjuna in cardiovascular disorders

American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions
Subir Kumar Maulik, Kewal K Talwar

Abstract

The bark of the tree Terminalia arjuna (Roxb.) is widely used in Indian medicine (Ayurveda) for various cardiovascular ailments. The bark has been reported to contain several bioactive compounds. Many experimental studies have reported its antioxidant, anti-ischemic, antihypertensive, and antihypertrophic effects, which have relevance to its therapeutic potential in cardiovascular diseases in humans. Several clinical studies have reported its efficacy mostly in patients with ischemic heart disease, hypertension, and heart failure. However, a major shortcoming in all these experimental and clinical studies is the absence of phytochemical standardization of the extracts. In addition, many clinical studies are poor in terms of design and methods used for generating safety data. This review discusses how to address all these issues for a scientific validation of this medicinal plant.

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Citations

Mar 7, 2014·Cardiology Research and Practice·Navjot KaurSamir Malhotra
Feb 8, 2014·Journal of Ethnobiology and Ethnomedicine·Mohammad Humayun KabirMohammed Rahmatullah
Nov 8, 2014·Journal of Traditional and Complementary Medicine·Shridhar Dwivedi, Deepti Chopra
Mar 19, 2016·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Subir K MaulikChandra K Katiyar
Nov 26, 2015·Environmental Toxicology and Pharmacology·Nafiseh Sadat AlamolhodaeiGholamreza Karimi
Aug 27, 2016·Pharmacognosy Magazine·Sonal Sharma, Neeta Shrivastava
Nov 3, 2020·Frontiers in Pharmacology·Gitishree DasJayanta Kumar Patra
Nov 12, 2020·Natural Products and Bioprospecting·Tarawanti VermaNagendra Singh Chauhan

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