Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa

Case Reports in Dermatological Medicine
Astrid-Helene Ravn JørgensenSimon Francis Thomsen

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).

References

Jul 10, 2014·The New England Journal of Medicine·Richard G LangleyUNKNOWN FIXTURE Study Group
Aug 19, 2015·The British Journal of Dermatology·G KellyB Kirby
Jan 4, 2017·Journal of the American Academy of Dermatology·Łukasz MatusiakJacek C Szepietowski
Jun 22, 2017·The British Journal of Dermatology·C C ZouboulisUNKNOWN European Hidradenitis Suppurativa Foundation Investigator Group
Jun 28, 2017·The British Journal of Dermatology·L ThorlaciusG B E Jemec

❮ Previous
Next ❯

Citations

Nov 16, 2019·The Journal of Experimental Medicine·Pascale ZwickyBurkhard Becher
Mar 3, 2020·The Journal of Dermatological Treatment·Kevin K Wu, Harry Dao
Feb 23, 2020·Expert Opinion on Biological Therapy·Monica Rosales SantillanAlexa B Kimball
Oct 31, 2019·International Journal of Dermatology·Nicoletta BernardiniConcetta Potenza
May 30, 2019·American Journal of Clinical Dermatology·Kelsey S FloodAlexa B Kimball
Jun 17, 2020·Dermatologic Therapy·Amelia GłowaczewskaŁukasz Matusiak

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Dermatologic Clinics
F William Danby, Lynette J Margesson
Seminars in Cutaneous Medicine and Surgery
Joyce T Yuan, Haley B Naik
Southern Medical Journal
T J BrownI F Orengo
© 2022 Meta ULC. All rights reserved