Therapeutic Role of Fat Injection in the Treatment of Recalcitrant Migraine Headaches

Plastic and Reconstructive Surgery
Bahman Guyuron, Navid Pourtaheri

Abstract

This study was designed to assess the safety and efficacy of site-specific fat injection for the treatment of refractory migraine headaches following medical or surgical treatment. A prospective cohort study was performed on consecutive patients who had migraine headaches with persistent symptoms after surgical decompression and were given therapeutic fat injections from September of 2012 to January of 2015 with 12 months' minimum follow-up. Clinical outcomes assessment included migraine frequency, intensity, duration, migraine headache index, and complications. A 50 percent or greater decrease in frequency, intensity, or duration was considered therapeutic success, whereas 10 percent or greater increase in migraine headache index was considered worsening of symptoms. Pairwise t tests were used to assess statistical significance (p < 0.05). Twenty-nine patients met inclusion criteria. All were female, with a mean age of 49.0 years (range, 21.5 to 72.5 years), and mean follow-up was 29.4 months (range, 12.3 to 49.5 months). Twenty patients (69.0 percent) experienced successful improvement; 12 (41.4 percent) experienced complete resolution. Five patients (17.2 percent) experienced subtherapeutic improvement, and four (13.8 percen...Continue Reading

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Mar 13, 2018·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Navid Pourtaheri, Bahman Guyuron

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Citations

Mar 1, 2019·Plastic and Reconstructive Surgery·Amy L StrongPaul S Cederna
Oct 28, 2019·Plastic and Reconstructive Surgery·Fabio CaviggioliMarco Klinger
Mar 3, 2021·Annals of Plastic Surgery·Isabel S RobinsonErnest S Chiu
May 22, 2021·Plastic and Reconstructive Surgery·Bahman Guyuron
May 22, 2021·Plastic and Reconstructive Surgery·Lisa GfrererWilliam Gerald Austen

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