Therapeutic strategies of thromboembolic events in patients with inflammatory bowel diseases: Two case reports

Medicine
Lei ZhuHong Shen

Abstract

Inflammatory bowel disease (IBD), including Crohn disease (CD) and ulcerative colitis (UC), is characterized by chronic inflammatory condition and immunological abnormalities, which probably develop into venous thromboembolic events (VTEs). VTE in IBD patients mostly occurs at deep venous thrombosis (DVT) and pulmonary embolism (PE). The complications are extremely important in clinical practice considering the high mortality rate. Hence, an early diagnosis of IBD and the control of complications play an important role in therapy of thromboembolic events (TEEs). Case 1 was a 31-year-old man with chronic UC who presented with signs of thromboembolism. Case 2 was a 43-year-old woman with CD complicated by fistulas. Computed tomography (CT) and digital subtraction angiography (DSA) of the patient (case 1) suggested a thrombus in cerebral vein. The patient (case 2) developed acute ischemia of her right arm; B ultrasonography revealed a thrombus in the distal of the right subclavian artery accompanied by stenosis. To lower blood viscosity and overcome the risk of deep thrombosis, the patient (case 1) was treated with a combination of low-molecular-weight heparin and dextran as anticoagulation. For the patient (case 2), anticoagulati...Continue Reading

References

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Jan 15, 2014·World Journal of Gastroenterology : WJG·Danuta OwczarekTomasz Mach
Oct 17, 2014·World Journal of Gastroenterology : WJG·Petros ZezosFred Saibil

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Citations

Mar 19, 2020·International Journal of Molecular Medicine·Jin ZhouRudan Zhou
Jul 2, 2021·Experimental Biology and Medicine·Zhichang PanYixin Shen

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Methods Mentioned

BETA
ESR

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