Therapeutic substitutions in the midst of new technology diffusion: The case of treatment for localized prostate cancer

Social Science & Medicine
Chan Shen, Ya-Chen Tina Shih

Abstract

Robotic surgical systems have become increasingly popular worldwide. Robotic assisted radical prostatectomies have been widely adopted in the treatment of localized prostate cancer, replacing the conventional open surgeries. However, it is not clear whether this was achieved by substitution within the same treatment type (i.e., replacing open surgeries with robotic-assisted surgeries) or substitution across treatment types (i.e., expanding the proportion of patients receiving surgery while crowding out other forms of treatment for localized prostate cancer). Given the large number of patients undergoing these procedures each year, it is important to study the impact of the fast diffusion of robotic surgical systems on the overall treatment pattern of localized prostate cancer. We addressed this question using state-level cancer epidemiology data (256 observations) extracted from 2002 to 2010 National Cancer Database, and supply-side variables (e.g. density of robotic surgical systems, urologists) obtained from Area Resource File as well as investor presentations posted at the website of the manufacturer of robotic surgical systems. Recognizing that the purchase decision of robotic systems is potentially endogenous, we used an o...Continue Reading

References

Sep 18, 2001·Health Affairs·D M Cutler, M McClellan
Jun 18, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jeffrey H BurkhardtJames A Hayman
Mar 26, 2003·Health Services Research·Kelly J DeversLawrence P Casalino
Jul 21, 2006·European Urology·Vincenzo FicarraWalter Artibani
Jan 11, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Neal J Meropol, Kevin A Schulman
May 10, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jim C HuNancy L Keating
May 16, 2008·Urologia Internationalis·Walter ArtibaniVincenzo Ficarra
Oct 15, 2009·JAMA : the Journal of the American Medical Association·Jim C HuNancy L Keating
Jan 12, 2010·The Journal of Sexual Medicine·Michaella M PrasadJim C Hu
Sep 8, 2010·The New England Journal of Medicine·Gabriel I Barbash, Sherry A Glied
Sep 25, 2010·Urologic Oncology·Evanguelos XylinasAlexandre de la Taille
Oct 15, 2010·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Mick P CouperBrian J Zikmund-Fisher
Mar 22, 2012·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Ya-Chen Tina ShihLinda S Elting
Sep 18, 2012·European Urology·Christian BolenzJim C Hu
Nov 21, 2012·The Journal of Urology·Bruce L JacobsBrent K Hollenbeck
Dec 12, 2012·Updates in Surgery·Eugenio Santoro, Vito Pansadoro
Feb 21, 2013·JAMA : the Journal of the American Medical Association·Jason D WrightDawn L Hershman
Feb 21, 2013·JAMA : the Journal of the American Medical Association·Joel S Weissman, Michael Zinner
May 15, 2013·The Journal of Urology·Florian R SchroeckBrent K Hollenbeck

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Citations

Mar 23, 2021·Journal of General Internal Medicine·Hansoo Ko, Sherry A Glied

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