PMID: 8939636Dec 1, 1996Paper

Therapeutic targeting of the p53 tumor suppressor gene

Current Opinion in Biotechnology
G A BeaudryM I Sherman

Abstract

The p53 tumor suppressor gene is a logical target for cancer therapy. Several therapeutic strategies can be envisioned based upon recent advances concerning structure and function of the p53 protein, its interaction with cellular and viral proteins and its roles in repairing DNA, regulating cell division and promoting apoptosis.

Citations

Apr 16, 1998·Springer Seminars in Immunopathology·R V Sionov, Y Haupt
May 3, 2003·Life Sciences·Louis W C ChowX Y Guan
Jan 13, 1998·Current Opinion in Biotechnology·R B Parekh, C Rohlff
Dec 23, 1999·Pathology Oncology Research : POR·H Abd El AllP Duvillard
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Mar 31, 1999·Proceedings of the National Academy of Sciences of the United States of America·M G Mateu, A R Fersht
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Jan 27, 2000·Cell·D Hanahan, R A Weinberg
Mar 18, 2004·British Journal of Cancer·H-J TangJ Lin
Nov 5, 1999·Neurosurgery·F F LangP J Tofilon

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