PMID: 6988023Mar 1, 1980Paper

Therapeutic use of immunoglobulins in children (author's transl)

W H Hitzig


The indications for immunoglobulin therapy in childhood have been well established for many years: prophylaxis is effective with single small doses, a full substitution needs multiple large applications. All other recommendations are ill-defined and result from wishful thinking rather than from solid clinical data. New is the possibility of safe i. v. Ig-application which could be realized through appropriate modification of gammaglobulin preparations. Some properties of the commercially available products are summarized. Our own experience with one of them is encouraging: as a matter of fact, fully effective gammaglobulin substitution is now possible in patients with antibody deficiency syndrome.


Jun 1, 1976·Journal of Biochemistry·Y MasuhoS Ishimoto
Oct 1, 1977·Journal of Biochemistry·Y FukumotoT Watanabe
Jun 3, 1972·Lancet·G N SmithP L Mollison
Jul 1, 1972·Vox Sanguinis·M Steinbuch
Apr 25, 1968·The New England Journal of Medicine·C A JanewayJ D Crain
May 29, 1969·The New England Journal of Medicine·P A BrunellB Kuo
Aug 1, 1969·American Journal of Diseases of Children·G M Schiff
Jan 31, 1974·The New England Journal of Medicine·A A GershonP A Brunell
Dec 6, 1969·British Medical Journal
Jan 1, 1962·Vox Sanguinis·S BARANDUNH ISLIKER


Related Concepts

Immunologic Deficiency Syndromes
Intravenous Injections
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