Several classes of antimicrobial agents (e.g., penicillins, cephalosporins, tetracyclines, chloramphenicol, and clindamycin) are useful in treatment of infections due to anaerobic bacteria. However, certain anaerobic bacteria have shown a striking resistance to antimicrobial agents. In vitro susceptibility tests are useful for selection of optimal therapy. The choice of agent depends, to some extent, on the organisms responsible for the infection. Bacteroides fragilis is the most commonly encountered anaerobe, and it is also the most resistant to antimicrobial agents. Other factors influencing the selection of therapy include pharmacologic characteristics, degree of bactericidal activity, and toxicity. Proper therapy for anaerobic infections often requires intensive antimicrobial therapy for a prolonged period. Surgical intervention, including drainage of abscesses and excision of necrotic tissue, is important.
Occurrence of Bacteroidaceae in vaginal secretions of healthy pregnant women and patients with colpitis
Serological evaluation of the outer membrane protein complexes of five saccharolytic intestinal Bacteroides species
Indirect serum haemagglutinating antibody response to black pigmented Bacteroides during experimental pure infections in rats
Meningitis due to Fusobacterium necrophorum subspecies necrophorum. Case report and review of the literature
Retrospective analysis of two hundred and twelve cases of bacteremia due to anaerobic microorganisms
The "clostridial effect" of selective decontamination of the human gut with trimethoprim/sulphamethoxazole in neutropenic patients
Identification and susceptibility patterns of anaerobic bacteria isolated from clinical specimens during a one-year period
Impact on peritonsillar infections and microflora of phenoxymethylpenicillin alone versus phenoxymethylpenicillin in combination with metronidazole
Anaerobic isolates in chronic recurrent suppurative otitis media. Treatment with carbenicillin alone and in combination with gentamicin
Host response to mixed anaerobic infection with Bacteroides melaninogenicus and Fusobacterium necrophorum
Predictors for anaerobic bacteraemia beyond the source of infection: retrospective, nested, case-control study
The prevalence of antibiotic resistance genes in Bacteroides fragilis group strains isolated in different European countries
Biochemical comparison of proteolytic enzymes present in rough- and smooth-surfaced capnocytophagas isolated from the subgingival plaque of periodontitis patients
Bacteroides fragilis adheres to laminin significantly stronger than Bacteroides thetaiotaomicron and other species of the genus
Indirect immunofluorescence microscopy for the identification of Actinomyces sp. in endodontic disease
The role of anaerobic bacteria in otitis media: microbiology, pathogenesis, and implications on therapy
Transcription activation of a UV-inducible Clostridium perfringens bacteriocin gene by a novel sigma factor
The prevalence of enterotoxin and antibiotic resistance genes in clinical and intestinal Bacteroides fragilis group isolates in Turkey
Complete nucleotide sequence and genetic organization of the bacteriocinogenic plasmid, pIP404, from Clostridium perfringens
Detection of Porphyromonas gingivalis, Porphyromonas endodontalis, Prevotella intermedia, and Prevotella nigrescens in chronic endodontic infection
Chemiluminescence of human leukocytes by black-pigmented Bacteroides strains from dental plaque and other sites
Phagocytosis of Bacteroides melaninogenicus and Bacteroides gingivalis in vitro by human neutrophils
Bactericidal effect of pooled human serum on Bacteroides melaninogenicus, Bacteroides asaccharolyticus and Actinobacillus actinomycetemcomitans
Identification of Bacteroides fragilisby a modified immuno polymerase chain reaction (mIPCR), using a specific monoclonal antibody
Typing of Clostridium perfringens strains by use of Random Amplified Polymorphic DNA (RAPD) system in comparison with zymotyping
Five-year retrospective epidemiological survey of anaerobic bacteraemia in a university hospital and rewiew of the literature
Roles of the host oxidative immune response and bacterial antioxidant rubrerythrin during Porphyromonas gingivalis infection
Attack of the nervous system by Clostridium perfringens Epsilon toxin: from disease to mode of action on neural cells
Species identification of clinical isolates of Bacteroides by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry
Enhancement of growth of group A beta-hemolytic streptococci in mixed infections with aerobic and anaerobic bacteria
Evaluation of the Rapid ID 32A system for identification of anaerobic Gram-negative bacilli, excluding the Bacteroides fragilis group
Evaluation of the RAPID ID 32A system for the identification of Bacteroides fragilis and related organisms
Isolation and characterization of Clostridium difficile associated with beef cattle and commercially produced ground beef
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease
Role of anaerobic bacteria in infections following tracheostomy, intubation, or the use of ventilatory tubes in children
Microbiology of acute sinusitis of odontogenic origin presenting with periorbital cellulitis in children
Integrating next-generation sequencing and traditional tongue diagnosis to determine tongue coating microbiome
Clostridium ramosum and beta hemolytic streptococci isolated from a child presenting with acute otitis media
Identification and Antimicrobial Susceptibility Testing of Anaerobic Bacteria: Rubik's Cube of Clinical Microbiology?
Rifaximin versus chlortetracycline in the short-term treatment of small intestinal bacterial overgrowth
Gene cloning shows the alpha-toxin of Clostridium perfringens to contain both sphingomyelinase and lecithinase activities
Common regulatory mechanism of expression and conjugative ability of a tetracycline resistance plasmid in Bacteroides fragilis
Absorbable vs. non-absorbable antibiotics in the treatment of small intestine bacterial overgrowth in patients with blind-loop syndrome
Effect of the presence of black pigmented Bacteroides of differing pathogenicity on the phagocytosis of Escherichia coli by rat polymorphonuclear leucocytes
Murdochiella asaccharolytica gen. nov., sp. nov., a Gram-stain-positive, anaerobic coccus isolated from human wound specimens
Bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
Alzheimer's Disease: MS4A
Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.
Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.
Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.
Genetic Screens in iPSC-derived Brain Cells
Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.
This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.
Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.
Pharmacology of Proteinopathies
This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.
Alignment-free Sequence Analysis Tools
Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.