PMID: 2497750May 1, 1989Paper

Therapy for systemic juvenile rheumatoid arthritis with gamma-interferon: a pilot study of nine patients

Arthritis and Rheumatism
W PerniceJ Brzoska

Abstract

Nine severely ill patients with a confirmed diagnosis of systemic juvenile rheumatoid arthritis were treated with recombinant gamma-interferon (gamma-IFN) in addition to the therapy they were previously receiving for their disease. Improvements in clinical symptoms were noted in 7 of the patients, and median laboratory values also showed a marked improvement after gamma-IFN treatment. A relapse occurred in 1 patient. The results of this study should stimulate further research on the use of gamma-IFN in systemic juvenile rheumatoid arthritis, particularly in determining the appropriate effective dosage.

References

Oct 1, 1987·Journal of Interferon Research·A Billiau
Jan 1, 1988·Scandinavian Journal of Immunology·T StolzenburgF J Wagenhaeuser
Jan 1, 1987·Clinical Immunology and Immunopathology·G C TsokosD B Magilavy
Jan 1, 1984·International Archives of Allergy and Applied Immunology·J B ZieglerR Penny
Jun 25, 1949·Journal of the American Medical Association·O STEINBROCKERR C BATTERMAN

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Citations

Jan 1, 1994·Biotherapy·L C Miller
Nov 24, 2007·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·A M Prieur, P Quartier
Jun 24, 2004·Expert Opinion on Pharmacotherapy·Andreas Otto Reiff
Nov 5, 1997·The Journal of Pediatrics·K T GallagherE R Stiehm
Jan 16, 1999·Baillière's Clinical Rheumatology·R Schneider, R M Laxer
Apr 10, 2015·Current Rheumatology Reports·Ignacio García-De LaTorre, Ignacio García-Valladares
Feb 2, 2008·Arthritis and Rheumatism·William J Koopman
Apr 1, 1990·Arthritis and Rheumatism·C A Gabriel, J E Levinson
Nov 9, 2000·Osteoarthritis and Cartilage·Y E HenrotinJ Y Reginster

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