Therapy of acute gastroenteritis: role of antibiotics

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
I Zollner-Schwetz, R Krause

Abstract

Acute infectious diarrhoea remains a very common health problem, even in the industrialized world. One of the dilemmas in assessing patients with acute diarrhoea is deciding when to test for aetiological agents and when to initiate antimicrobial therapy. The management and therapy of acute gastroenteritis is discussed in two epidemiological settings: community-acquired diarrhoea and travellers' diarrhoea. Antibiotic therapy is not required in most patients with acute gastroenteritis, because the illness is usually self-limiting. Antimicrobial therapy can also lead to adverse events, and unnecessary treatments add to resistance development. Nevertheless, empirical antimicrobial therapy can be necessary in certain situations, such as patients with febrile diarrhoeal illness, with fever and bloody diarrhoea, symptoms persisting for >1 week, or immunocompromised status.

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Citations

Dec 8, 2015·Expert Review of Anti-infective Therapy·Christoph Lübbert
Feb 25, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F Allerberger
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Apr 27, 2021·Emerging Infectious Diseases·Wen-Qiang HeBette Liu
Aug 27, 2021·Frontiers in Microbiology·Erin MilnerKatharine Segars

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