Nov 15, 1989

Therapy of chronic idiopathic thrombocytopenic purpura in adults

Blood
P Berchtold, R McMillan

Abstract

Chronic ITP is a common hematologic illness. Approximately three fourths of the patients respond to corticosteroids or splenectomy and need no further treatment. Patients refractory to these two therapeutic approaches are relatively resistant to present forms of treatment and are at much greater risk for morbidity and mortality. Future clinical studies evaluating therapy in this refractory group would be best performed in a cooperative group setting in which large numbers of patients could be treated in a prospective randomized manner.

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Mentioned in this Paper

Monoclonal Antibodies
Corticosteroid-Binding Globulin Deficiency
Pregnancy Complications, Hematologic
Vinca Alkaloids
Adrenal Cortex Hormones
Azathioprine Sulfate
Magnorbin
Gamma globulin
Autoimmune Diseases
Cyclosporins

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