PMID: 11929391Apr 4, 2002Paper

There are no reliable symptoms for erosive oesophagitis and Barrett's oesophagus: endoscopic diagnosis is still essential

Alimentary Pharmacology & Therapeutics
B AvidanS J Sontag

Abstract

To evaluate the sensitivity and specificity of different symptoms in erosive reflux oesophagitis and Barrett's oesophagus. The presence of reflux symptoms was compared between a case population of 306 patients with endoscopically determined erosive reflux oesophagitis, 235 patients with biopsy-proven Barrett's oesophagus and a control population of 198 subjects without reflux disease. Heartburn at any time and heartburn at night represented the only two symptoms to be simultaneously sensitive and specific. Symptoms that were induced by various foods, such as fat, tomato, chocolate, citrus or spices, tended to cluster in the same sub-group of patients. Similarly, heartburn induced by exercise, lying down or bending over tended to occur in the same sub-groups. The frequency of symptoms was influenced more by the presence of mucosal erosions than by the presence of Barrett's oesophagus. Reflux symptoms occurred more frequently in the presence rather than the absence of Barrett's oesophagus, and in long segment rather than short segment of Barrett's mucosa. Endoscopic inspection of the oesophageal mucosa remains the only certain method by which to reliably diagnose erosive reflux oesophagitis and Barrett's oesophagus.

References

Nov 1, 1976·The American Journal of Digestive Diseases·O T NebelD O Castell
Jan 1, 1991·Scandinavian Journal of Gastroenterology. Supplement·I KääriäinenM Siurala
Jan 27, 1990·Lancet·A G KlauserS A Müller-Lissner
Mar 1, 1991·Gastroenterology·S Sloan, P J Kahrilas
Jan 1, 1991·Scandinavian Journal of Gastroenterology·M RuthN Sandberg
Jun 23, 1989·JAMA : the Journal of the American Medical Association·C S ClarkD O Castell
Jan 1, 1989·Digestive Diseases and Sciences·S MattioliG Gozzetti
Sep 1, 1988·Digestive Diseases and Sciences·G J WienerJ E Richter
Aug 1, 1987·Scandinavian Journal of Gastroenterology·F JohnssonL Greiff
Mar 18, 1999·The New England Journal of Medicine·J LagergrenO Nyrén

❮ Previous
Next ❯

Citations

Nov 5, 2003·Gastrointestinal Endoscopy·G Richard LockeNicholas J Talley
Apr 3, 2007·Southern Medical Journal·Alan C Moss, Ciarán P Kelly
Apr 24, 2010·Applied Immunohistochemistry & Molecular Morphology : AIMM·Marcelo BinatoMaria Isabel Edelweiss
Nov 19, 2010·World Journal of Gastroenterology : WJG·Shigeyuki KobayashiTooru Shimosegawa
Aug 21, 2013·Journal of Obesity·Michael LaffinShahzeer Karmali
Mar 19, 2005·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·R E Sampliner
Oct 1, 2004·Alimentary Pharmacology & Therapeutics·A Sonnenberg
Sep 21, 2006·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·R DickmanR Fass
Jan 19, 2005·The American Journal of Gastroenterology·Kenneth R DeVaultUNKNOWN American College of Gastroenterology
Jun 19, 2003·Gastroenterology·Spyros Michopoulos
Aug 28, 2004·The American Journal of Gastroenterology·Joachim LabenzPeter Malfertheiner
Aug 25, 2006·The American Journal of Gastroenterology·Nimish VakilUNKNOWN Global Consensus Group
Oct 17, 2007·Digestive Diseases and Sciences·P A C GatenbyA Watson
Jan 8, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·H MiwaJ Koseki
Mar 24, 2009·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·M BinatoM I Edelweiss
Jan 12, 2010·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·T OshimaH Miwa
Aug 5, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kyle A PerryBlair A Jobe
Feb 5, 2009·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Xia ChenKiao-Hua Hou
Feb 19, 2009·Alimentary Pharmacology & Therapeutics·P A C GatenbyA Watson
Mar 1, 2005·The Journal of Nutrition·Vijay GanjiUNKNOWN Third National Health and Nutrition Examination Survey, 1998-1994
Oct 5, 2011·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·R A SawayaF K Friedenberg
Jan 27, 2009·Journal of Clinical Gastroenterology·Ki-Nam ShimUNKNOWN H. pylori and GERD Study Group of Korean College of Helicobacter and Upper Gastrointestinal Research
Sep 15, 2020·European Journal of Gastroenterology & Hepatology·Andrea BallaDanilo Badiali
Jul 6, 2004·Gastroenterology·Prateek SharmaUNKNOWN AGA Chicago Workshop
Aug 15, 2003·Gastrointestinal Endoscopy Clinics of North America·M Brian Fennerty

❮ Previous
Next ❯

Related Concepts

Related Feeds

Barrett Esophagus

Barrett’s esophagus if a serious complication of gastroesophageal reflux disease during which the normal esophageal lining changes to tissue that resembles intestinal lining. Here is the latest research.