There Is No Association between Coeliac Disease and Autoimmune Pancreatitis

Nutrients
Giulia De MarchiRachele Ciccocioppo

Abstract

Autoimmune pancreatitis (AIP) is a rare disorder whose association with coeliac disease (CD) has never been investigated, although CD patients display a high prevalence of both endocrine and exocrine pancreatic affections. Therefore, we sought to evaluate the frequency of CD in patients with AIP and in further medical pancreatic disorders. The screening for CD was carried out through the detection of tissue transglutaminase (tTG) autoantibodies in sera of patients retrospectively enrolled and divided in four groups: AIP, chronic pancreatitis, chronic asymptomatic pancreatic hyperenzymemia (CAPH), and control subjects with functional dyspepsia. The search for anti-endomysium autoantibodies was performed in those cases with borderline or positive anti-tTG values. Duodenal biopsy was offered to all cases showing positive results. One patient out of 72 (1.4%) with AIP had already been diagnosed with CD and was following a gluten-free diet, while one case out of 71 (1.4%) with chronic pancreatitis and one out of 92 (1.1%) control subjects were diagnosed with de novo CD. No cases of CD were detected in the CAPH group. By contrast, a high prevalence of cases with ulcerative colitis was found in the AIP group (13.8%). Despite a mutual ...Continue Reading

References

Jun 1, 1995·Journal of Clinical Gastroenterology·P RajvanshiS Gupta
Dec 14, 1999·Clinical and Experimental Immunology·G BruscoG R Corazza
May 31, 2001·European Journal of Clinical Investigation·J Walkowiak, K H Herzig
Jun 11, 2002·Gastroenterology·Susi Martucci, Gino Roberto Corazza
Apr 18, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Antonio CarroccioGiuseppe Iacono
May 9, 2006·Gastroenterology·George F LongstrethRobin C Spiller
Sep 7, 2006·Journal of Pediatric Gastroenterology and Nutrition·Sanda Nousia-ArvanitakisMichael Karamouzis
May 24, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Yoh ZenYasuni Nakanuma
Jun 5, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Gino Roberto CorazzaFrancesco Donato
Aug 19, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Jonas F LudvigssonAnders Ekbom
Jul 5, 2008·Journal of Gastroenterology·Makoto OtsukiUNKNOWN Research Committee of Intractable Pancreatic Diseases provided by the Ministry of Health, Labour and Welfare of Japan and th
Aug 5, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·John S Leeds, David S Sanders
Dec 17, 2008·The New England Journal of Medicine·Deborah J SmythJohn A Todd
Feb 25, 2009·Inflammatory Bowel Diseases·Karthik RaviEdward V Loftus
Mar 18, 2011·Pancreas·Tooru ShimosegawaUNKNOWN International Association of Pancreatology
Sep 29, 2011·European Journal of Gastroenterology & Hepatology·Ibrahim MasoodiAbed H Al-Lehibi
May 16, 2012·The American Journal of Gastroenterology·Antonio AmodioLuca Frulloni
Jul 18, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Omid Sadr-AzodiJonas F Ludvigsson
Aug 18, 2012·International Journal of Rheumatology·Kazushige UchidaKazuichi Okazaki
Feb 22, 2013·Journal of Clinical Gastroenterology·Sang Hyoung ParkJin-Ho Kim
Feb 23, 2013·American Journal of Clinical Pathology·Katherine M CebeMaria Westerhoff
Apr 30, 2013·Gastroenterology·Dhiraj Yadav, Albert B Lowenfels
Jul 1, 2014·Journal of Pediatric Gastroenterology and Nutrition·Riccardo Troncone, Valentina Discepolo
Nov 25, 2014·Recent Patents on Inflammation & Allergy Drug Discovery·Raffaele Pezzilli
Mar 17, 2015·Gastroenterology·Phil A HartSuresh T Chari
Aug 12, 2015·Nature Reviews. Gastroenterology & Hepatology·Daniel A LefflerAlessio Fasano
Aug 26, 2015·Nature Reviews. Gastroenterology & Hepatology·Knut E A Lundin, Cisca Wijmenga
Nov 26, 2015·Seminars in Immunology·J Stamnaes, L M Sollid
Feb 24, 2016·World Journal of Gastroenterology : WJG·Sinead N DugganKevin C Conlon
Apr 6, 2016·The American Journal of Gastroenterology·Valeria D'ArgenioLucia Sacchetti
Aug 31, 2016·Journal of Pediatric Gastroenterology and Nutrition·Batia Weiss, Orit Pinhas-Hamiel
Aug 2, 2017·Lancet·Benjamin LebwohlPeter H R Green
Mar 20, 2018·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Prashant SinghGovind K Makharia

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