Thermal acclimatization of hepatic polysubstrate monooxygenase and UDP-glucuronosyltransferase of mature rainbow trout (Salmo gairdneri)

The Journal of Experimental Zoology
U Koivusaari

Abstract

The thermal acclimatization of hepatic cytochrome P-450-dependent polysubstrate monooxygenase (PSMO) and UDP-glucuronosyltransferase of mature rainbow trout (Salmo gairdneri) was studied. The results indicate that the PSMO system, 7-ethoxycoumarin and benzo(a)pyrene as substrates, shows almost ideal acclimatization pattern in autumn during water cooling. The enzyme activities were identical if measurements were carried out at acclimatization (=environmental) temperatures which were 20 degrees C in August and 5 degrees C in November. If a constant incubation temperature (18 degrees C) was used, the PSMO activities were significantly higher in cold (5 degrees C)-acclimatized fish. The acclimatization process could be seen both in specific and total activities. The content of cytochrome P-450 remains at constant level from August to November. In early summer during water warming the PSMO activities increased considerably in both sexes in all incubation conditions. The specific and total UDP-glucuronosyltransferase activities were significantly higher in warm-acclimatized fish both in the autumn and in the spring if the activities were measured at environmental temperature. No differences could be detected if the measurements were ...Continue Reading

References

Apr 1, 1978·Analytical Biochemistry·A Aitio
Aug 1, 1977·Biochemical Pharmacology·C N StathamJ J Lech
Jul 1, 1974·Physiological Reviews·J R Hazel, C L Prosser
Jun 1, 1981·General and Comparative Endocrinology·T Hansson, J A Gustafsson
Apr 1, 1981·International Journal of Andrology·V Hansson

❮ Previous
Next ❯

Citations

Jun 1, 1987·Biochimie·J L Riviere, F Cabanne
Jan 1, 1985·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·T AnderssonL Förlin
Mar 7, 1998·Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology·D MarionnetP Deschaux
Feb 8, 2000·Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology·D RoniszL Förlin
Jun 25, 2002·Journal of Toxicology and Environmental Health. Part a·Camille R El-ZahrLawrence R Curtis
Apr 1, 1987·Environmental Health Perspectives·M O James
Mar 16, 2013·Environmental Science and Pollution Research International·Margaret O James, Kevin M Kleinow
Jan 1, 1997·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·J BeyerA Goksøyr
Jan 1, 1996·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·B K Gadagbui, A Goksrøyr
Mar 16, 2007·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Patrick N FitzsimmonsJohn W Nichols
Oct 19, 2006·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Kevin M KleinowMatthew E McCarrol
Jan 1, 1989·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·J Bach, J Snegaroff
Oct 3, 1998·Ecotoxicology and Environmental Safety·D MarionnetP Deschaux
Jan 11, 2020·Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics·Yan ZhaoJinling Zhao

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.