Thermal and mechanical pain sensitization in patients with osteoarthritis of the knee

Physiotherapy Theory and Practice
Debora Bevilaqua-GrossiAnamaria Oliveira

Abstract

The aim was to assess sensitization using quantitative sensory testing in mechanical and thermal modes in individuals with and without osteoarthritis (OA) of the knee. Pain thresholds were correlated with functionality, symptoms of depression and intensity of pain. Thirty control volunteers and 30 patients with OA of the knee were assessed. Punctate pain thresholds using Von Frey filaments and thermal pain thresholds using a Thermal Sensory Analyzer were evaluated in the periarticular region of the knee and forearm. Using a digital pressure algometer, pressure pain thresholds were assessed in the periarticular region of the knee and on the root exit zone on the lumbar and sacral spine. Punctate, pressure, and thermal pain thresholds differed significantly between participants with and without OA (p < 0.05). Values in those with OA were consistent with pain sensitization. Pressure pain thresholds also showed moderate and negative correlations with data on functionality, symptoms of depression and intensity of pain (-0.36 < r > -0.56), contributing up to 30% of their variability. Allodynia and hyperalgesia were demonstrated in the OA group, suggesting central sensitization in patients with mild to moderate severity of joint damag...Continue Reading

References

Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Dec 1, 1957·Annals of the Rheumatic Diseases·J H KELLGREN, J S LAWRENCE
Nov 19, 2003·The Journal of Pain : Official Journal of the American Pain Society·J Amir HendianiTerry McNearney
Feb 27, 2007·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Jessica M McIlvaneStephen A Paget
Mar 30, 2010·Osteoarthritis and Cartilage·B L WiseD J Hunter
Apr 27, 2010·Pain·Lars Arendt-NielsenThomas Graven-Nielsen
Dec 28, 2010·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Wen-Rui HouMing Xiang
Nov 29, 2011·Rheumatology·Vikki WyldePaul Dieppe
Dec 3, 2011·Archives of Physical Medicine and Rehabilitation·Adriaan LouwEmilio J Puentedura
Dec 21, 2011·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Laura ManeaDean McMillan
Jul 17, 2012·Current Rheumatology Reports·Hans-Georg Schaible
Aug 11, 2012·Current Rheumatology Reports·Susan L MurphyDaniel J Clauw
Feb 9, 2013·Physical Therapy·Enrique Lluch GirbésCarlos López Cubas
Sep 10, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Yenisel Cruz-Almeida, Roger B Fillingim
Sep 11, 2013·Annals of Neurology·Ralf BaronAnthony H Dickenson
Apr 5, 2014·European Journal of Pain : EJP·E LluchJ Van Oosterwijck
May 29, 2014·The Clinical Journal of Pain·Barbara RakelKathleen A Sluka
Mar 10, 2015·Osteoarthritis and Cartilage·C FingletonC Doody

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Citations

Oct 30, 2020·Journal of Pain Research·Chong PengWen Shen
Oct 2, 2020·American Journal of Physical Medicine & Rehabilitation·Mohammadreza AmiriDinesh Kumbhare
Sep 29, 2021·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Jonathan RankinLisa C Carlesso

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