Thermal control of brown adipose tissue in 18F-FDG PET

Journal of Nuclear Medicine Technology
Annah SkillenJanelle M Wheat

Abstract

The visualization of hypermetabolic brown adipose tissue (BAT) on (18)F FDG PET lowers the efficacy of PET and has been linked with the environmental temperature of the patient before presentation. The objective of this paper is to investigate the effectiveness of thermal control on BAT and (18)F-FDG PET. Three hundred patients undergoing (18)F-FDG PET were defined by 1 of 2 groups. Group A consisted of 150 consecutive patients from August to October 2009 (spring). Group B consisted of 150 consecutive patients from December to February 2010 (summer). In addition to normal preparation, group B received instructions to dress warmly and was warmed during the uptake period of their scan. Images were assessed for the presence of BAT. Standardized uptake value data were collected and compared. BAT was present in 9.3% of patients; 15.3% of patients that were not warmed (group A) demonstrated BAT, and this was reduced to 3.3% in the group that underwent warming (group B) (P = 0.0005). BAT was more common in men (10.9%) than women (6.8%), and women responded better to warming. Younger patients were more likely to demonstrate BAT (P < 0.001). No significant relationship between BAT and height, weight, or body mass index was found. The mo...Continue Reading

Citations

Feb 11, 2014·European Journal of Nuclear Medicine and Molecular Imaging·Matthias BauwensBoudewijn Brans
Dec 20, 2014·American Journal of Otolaryngology·Christopher H RassekhBarbara S Ducatman
Nov 13, 2014·Hormone Molecular Biology and Clinical Investigation·James LawMichael E Symonds
Apr 10, 2020·Experimental Physiology·Katharina SchnablMartin Klingenspor
Apr 19, 2018·Contrast Media & Molecular Imaging·Ryuichi NishiiToshinori Hirai
Jan 21, 2017·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Carlos GerngroßTobias Fromme
Mar 11, 2017·Journal of Nuclear Medicine Technology·Justine CousinsGeoff Currie
Jun 6, 2021·Endocrinology·Katharina SchnablMartin Klingenspor

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