PMID: 6109765Feb 1, 1981Paper

Thermal denaturation of native striatal tyrosine hydroxylase: increased thermolability of the phosphorylated form of the enzyme

Journal of Neurochemistry
M A LazarJ D Barchas

Abstract

Tyrosine hydroxylase was purified from bovine corpus striatum. The native enzyme had a half-life of 15 +/- 3 min at 50 degrees C. Phosphorylation of tyrosine hydroxylase with protein kinase purified from both corpus striatum and heart activated the enzyme, but activity was rapidly lost with additional preincubation of the enzyme at 30 degrees C. Thermal denaturation studies indicated that phosphorylated tyrosine hydroxylase had a half-life of 5 +/- 2 min at 50 degrees C

References

Oct 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·T H JohD J Reis
Aug 19, 1974·Biochemical and Biophysical Research Communications·T Lloyd, S Kaufman
Nov 1, 1971·Journal of Neurochemistry·T NagatsuI Nagatsu
Jan 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·P R VullietN Weiner

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Citations

Sep 28, 2005·Biochemical Genetics·Wendi S NeckameyerT J Paradowski
Jan 1, 1983·Neurochemistry International·M A LazarJ D Barchas
May 29, 2014·Journal of Neural Transmission·Izel TekinKent E Vrana
Dec 1, 2004·Journal of Neurochemistry·Peter R DunkleyPhillip W Dickson
Jun 1, 1983·Journal of Neurochemistry·K E Vrana, R Roskoski
Jul 1, 1991·Journal of Neurochemistry·S Okuno, H Fujisawa
Mar 1, 1987·Journal of Neurochemistry·R RoskoskiD B Glass
Dec 28, 1983·Biochemical and Biophysical Research Communications·D M Kuhn, W Lovenberg
Feb 11, 1991·Protein Expression and Purification·L G Gahn, R Roskoski
Nov 7, 1996·Chemical Reviews·T. Joseph Kappock, John P. Caradonna

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