Thermal stability and haemolytic effects of depolymerized guar gum derivatives

Journal of Food Science and Technology
Majid HussainAneela Hameed

Abstract

The purpose of current study was to purify and partially depolymerize guar gum by β-mannanase, HCl, Ba(OH)2 actions and subjected to inspect compositional, thermogravimetric analysis (TGA) and haemolytic activity. Chemical composition revealed mannose and galactose ratio remained un-altered even after process of purification and hydrolysis. TGA thermograms affirmed initial and final decomposition temperature in various zones. Major decomposition stages apparently revealed partially hydrolyzed guar gum (PHGG) exhibited better heat stable properties having more zones of degradation than crude one. Furthermore, all guar fractions (2.5-250 mg/mL) were subjected to haemolysis to evaluate toxic effects during process of hydrolysis. The crude and hydrolyzed guar galactomannans exhibited minor haemolytic activity (1.9 ± 0.03-7.24 ± 0.02%) when compared to 0.1% Triton-X 100 (100% haemolysis) showing no toxic effects to human RBC's. Conclusively, hydrolyzed guar-galactomannans are safe and can be used in food products with improved heat stability.

References

May 1, 1985·The American Journal of Clinical Nutrition·M E McIvorA I Mendeloff
Nov 17, 2001·Biomacromolecules·Y Cheng, R K Prud'homme
Feb 1, 2003·International Journal of Biological Macromolecules·Yu ChengRobert K Prud'homme
Jun 5, 2003·Nutrition·Joanne L Slavin, Norman A Greenberg
Sep 28, 2006·Journal of Agricultural and Food Chemistry·Masahiro KurakakeToshiaki Komaki
May 29, 2007·International Journal of Biological Macromolecules·Pablyana L R CunhaJudith P A Feitosa
Jan 31, 2008·Journal of Clinical Biochemistry and Nutrition·Seon-Joo YoonLekh Raj Juneja
Mar 14, 2012·International Journal of Biological Macromolecules·Deepak MudgilB S Khatkar
Dec 5, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Muhammad RiazUmer Rashid
Jan 26, 2013·Journal of Agricultural and Food Chemistry·John W FinleyGeorge C Fahey
Mar 19, 2013·Carbohydrate Polymers·Adriana F LubamboCyro Ketzer Saul
Sep 27, 2014·International Journal of Biological Macromolecules·Majid HussainMuhammad Shahid

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