Thermodynamic and Kinetic Parameters for Calcite Nucleation on Peptoid and Model Scaffolds: A Step toward Nacre Mimicry

Crystal Growth & Design
Anne Rath NielsenKarina Sand

Abstract

The production of novel composite materials, assembled using biomimetic polymers known as peptoids (N-substituted glycines) to nucleate CaCO3, can open new pathways for advanced material design. However, a better understanding of the heterogeneous CaCO3 nucleation process is a necessary first step. We determined the thermodynamic and kinetic parameters for calcite nucleation on self-assembled monolayers (SAMs) of nanosheet-forming peptoid polymers and simpler, alkanethiol analogues. We used nucleation rate studies to determine the net interfacial free energy (γnet) for the peptoid-calcite interface and for SAMs terminated with carboxyl headgroups, amine headgroups, or a mix of the two. We compared the results with γnet determined from dynamic force spectroscopy (DFS) and from density functional theory (DFT), using COSMO-RS simulations. Calcite nucleation has a lower thermodynamic barrier on the peptoid surface than on carboxyl and amine SAMs. From the relationship between nucleation rate (J0) and saturation state, we found that under low-saturation conditions, i.e. <3.3 (pH 9.0), nucleation on the peptoid substrate was faster than that on all of the model surfaces, indicating a thermodynamic drive toward heterogeneous nucleatio...Continue Reading

References

Sep 15, 1988·Physical Review A: General Physics·A D Becke
Jun 15, 1986·Physical Review. B, Condensed Matter·J P Perdew
Jun 20, 1996·Chemical Reviews·Abraham Ulman
Aug 25, 2004·Langmuir : the ACS Journal of Surfaces and Colloids·Dorothy M Duffy, John H Harding
Jul 21, 2006·The Journal of Physical Chemistry. B·A Markus TravailleHerman van Kempen
Feb 23, 2008·Science·Lorenz J BondererLudwig J Gauckler
Apr 13, 2010·Nature Materials·Ki Tae NamRonald N Zuckermann
Sep 24, 2011·Journal of the American Chemical Society·Babak SaniiRonald N Zuckermann
Jan 1, 2010·Annual Review of Chemical and Biomolecular Engineering·Andreas KlamtWolfgang Arlt
Jul 26, 2012·Nature Communications·Alexander FinnemoreUllrich Steiner
Aug 8, 2012·Proceedings of the National Academy of Sciences of the United States of America·Raymond W FriddleJames J De Yoreo
May 22, 2013·Proceedings of the National Academy of Sciences of the United States of America·Anthony J GiuffrePatricia M Dove
Jun 1, 2013·ACS Nano·Jing Sun, Ronald N Zuckermann
Sep 11, 2013·ACS Nano·Gloria K OlivierRonald N Zuckermann
Nov 6, 2013·Methods in Enzymology·Michael H Nielsen, Jonathan R I Lee
Nov 12, 2013·Biophysical Journal·Hédi SoulaHugues Berry
Jan 18, 2014·Proceedings of the National Academy of Sciences of the United States of America·Laura M HammPatricia M Dove
May 16, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·M P AnderssonS L S Stipp
Sep 10, 2014·Proceedings of the National Academy of Sciences of the United States of America·Ellen J RobertsonGeraldine L Richmond
Oct 27, 2014·Nature Materials·Ulrike G K WegstRobert O Ritchie
May 30, 2015·Chemical Communications : Chem Comm·Joo Myung V JunRonald N Zuckermann
Oct 8, 2015·Nature·Ranjan V MannigeStephen Whitelam
Aug 12, 2014·Journal of Chemical Theory and Computation·M P AnderssonS L S Stipp
Oct 12, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Daniel J MurrayRonald N Zuckermann

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Methods Mentioned

BETA
chips
X-ray
flame atomic absorption spectroscopy
AFM

Software Mentioned

PHREEQC
Turbomole
COSMO
COMSO
RS

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