PMID: 7992910Dec 1, 1994Paper

Thermoregulatory and anesthetic-induced alterations in the differences among femoral, radial, and oscillometric blood pressures

J M HynsonJ A Katz


A decrease in radial artery blood pressure relative to central arterial blood pressure is commonly associated with the rewarming phase of cardiopulmonary bypass. Decreased hand vascular resistance has been suggested as a possible mechanism. Although decreased blood viscosity due to hemodilution may contribute to decreased hand vascular resistance, thermoregulatory vascular responses to core hyperthermia also may be important. Seven healthy volunteers were studied. Volunteers first were cooled until thermoregulatory vasoconstriction was evident. Next, each was warmed until intense sweating developed. After a cool-down period, general anesthesia was induced with propofol and N2O. Femoral artery pressure (a surrogate for central arterial pressure) and radial artery and oscillometric (brachial artery) pressures were compared during each of six defined thermoregulatory and anesthetic study conditions. To determine the effect of hand vascular resistance on blood pressure differences, measurements were compared before and after occlusion of hand blood flow. Upper-extremity blood flow was evaluated by forearm and fingertip plethysmography and laser Doppler flowmetry. Forearm, fingertip, and cutaneous blood flow increased significantly ...Continue Reading


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Sep 1, 1996·Anesthesia and Analgesia·S P NebbiaD I Sessler
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