PMID: 9534201Apr 16, 1998Paper

Thickened gastric mucosal capillary wall: a histological marker for portal hypertension

Pathology
Vatsala MisraManisha Dwivedi

Abstract

To evaluate whether the diameter or thickness of the wall of mucosal capillaries in the stomach could be a useful histological marker of portal hypertension, gastric mucosal biopsies were taken from the fundus and antrum of 73 patients with cirrhosis of the liver and 64 healthy volunteers. The mean +/- SD diameter of mucosal capillaries in the fundus of patients was not significantly different from that in the control group (59.4 +/- 16.8 microns vs 53.5 +/- 16.5 microns, respectively; P = NS). However, the mean +/- SD diameter of the antral mucosal capillaries was significantly greater in patients compared to controls (61.3 +/- 18.1 microns vs 47.6 +/- 12.7 microns, respectively; P < 0.001). The mean +/- SD thickness of the fundal and antral capillary wall in the patients group (6.8 +/- 2.4 microns and 7.2 +/- 2.4 microns, respectively) was significantly greater than that in the control group (3.5 +/- 1.5 microns and 3.3 +/- 1.5 microns, respectively) (P < 0.001 for each). The overall diagnostic accuracy of antral mucosal capillary diameter to diagnose portal hypertension was 50%, while that of thickened fundal and antral mucosal capillary wall was 84% and 85%, respectively. It is concluded that the gastric mucosal capillary w...Continue Reading

References

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Citations

Nov 24, 2004·Gastrointestinal Endoscopy·Sri Prakash MisraManisha Gupta
Feb 27, 2003·Journal of Gastroenterology and Hepatology·Vatsala MisraVineeta Kumar
Jul 3, 2015·Liver International : Official Journal of the International Association for the Study of the Liver·Eladio Rodriguez-DiazSatish K Singh
Sep 28, 2005·Gastrointestinal Endoscopy·Ricardo J Marrero, Jamie S Barkin
Oct 29, 2000·The American Journal of Gastroenterology·C J Gostout
May 9, 2007·Revista Da Sociedade Brasileira De Medicina Tropical·Mario Ribeiro de Melo-JúniorNicodemos Teles de Pontes-Filho
Sep 5, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Swan SpecchiMatthew Paek
Jun 18, 2021·Indian Journal of Pathology & Microbiology·Vatsala MisraSri Praksh Misra

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