Thickened inner hypoechoic layer of the gallbladder wall in the diagnosis of anomalous pancreaticobiliary ductal union with endosonography

Gastrointestinal Endoscopy
S TannoY Kohgo

Abstract

An anomalous pancreaticobiliary ductal union (APBD) is a high-risk factor for biliary tract carcinoma, which often is not diagnosed before overt malignancy. The early detection of APBD is therefore clinically important. We evaluated the gallbladder wall in APBD patients with endoscopic ultrasonography. Clinicopathologic features and ultrasonographic findings of the gallbladder in 33 consecutive patients with APBD between 1986 and 1995 were studied in relation to two subtypes of APBD, that is, undilated (n = 17) and dilated (n = 16). The gallbladder wall was evaluated with conventional ultrasonography and/or endoscopic ultrasonography. Histologic examinations of 25 resected gallbladders were made. Fourteen of the seventeen patients with undilated type APBD (82%) had diffuse thickened gallbladder wall of 4 mm or more, whereas 5 of the 16 with dilated type (31%) had this finding (p < 0.01). The thickened gallbladder wall consisted sonographically of two layers: diffuse thickened inner hypoechoic layer and outer hyperechoic layer. Mucosal hyperplasia was histologically found in 8 of 9 cases (89%) with thickened inner hypoechoic layer on endoscopic ultrasonography. Mucosal hyperplasia was observed in 10 of 11 undilated type APBD cas...Continue Reading

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Citations

Jun 23, 2012·Journal of Gastroenterology·Terumi KamisawaUNKNOWN Japanese Study Group on Pancreaticobiliary Maljunction
Dec 8, 2011·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Yi-Lei DengXian-Ze Xiong
Oct 5, 2001·Journal of Pediatric Surgery·M D StringerG Lealman
Jan 18, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ayako OnoKaori Togashi

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