Thinking Well: A randomised controlled feasibility study of a new CBT therapy targeting reasoning biases in people with distressing persecutory delusional beliefs

Journal of Behavior Therapy and Experimental Psychiatry
Helen WallerPhilippa Garety

Abstract

Delusional beliefs with persecutory content are common in psychosis, but difficult to treat. Interventions targeting hypothesised causal and maintaining factors have been proposed as a way of improving therapy. The current study is a feasibility randomised controlled trial of the 'Thinking Well (TW)' intervention: This novel approach combines the recently developed Maudsley Review Training Programme (MRTP), with additional, focussed cognitive-behavioural therapy sessions. 31 participants with distressing persecutory delusions and schizophrenia spectrum disorders were randomised to TW or to treatment as usual in a 2:1 ratio. Participants completed outcome assessments at 0 (baseline), 1 (post-MRTP), 6 (post-TW) and 8 (follow-up) weeks. Key outcomes included belief flexibility, paranoia, and delusional conviction and distress. Participants allocated to TW completed the MRTP package and four CBT sessions with a clinical psychologist. Recruitment proved feasible. Participants reported the intervention was relevant and had resulted in positive changes in thinking and mood, which they could use in everyday life. Treatment effects were moderate-large for key outcomes including belief flexibility, paranoia conviction and distress. The a...Continue Reading

References

Jul 1, 1993·The British Journal of Psychiatry : the Journal of Mental Science·S WesselyP J Taylor
Aug 11, 2004·Journal of Consulting and Clinical Psychology·Daniel FreemanGraham Dunn
Aug 25, 2005·Journal of Abnormal Psychology·Philippa A GaretyRobert Dudley
Dec 25, 2007·Annual Review of Psychology·Jonathan St B T Evans
Jun 13, 2009·Schizophrenia Bulletin·Kerry RossPhilippa Garety
Sep 13, 2011·Schizophrenia Research·Daniel Freeman
Dec 12, 2012·Schizophrenia Bulletin·Daniel FreemanPhilippa Garety
Oct 29, 2013·Schizophrenia Bulletin·Steven MarwahaDaniel Freeman
Nov 5, 2013·Schizophrenia Research·Steffen MoritzDaniela Roesch-Ely
Nov 5, 2013·The British Journal of Psychiatry : the Journal of Mental Science·P A Garety, D Freeman
Feb 15, 2014·The American Journal of Psychiatry·David Trevor TurnerPim Cuijpers
May 29, 2014·Clinical Psychology Review·Steffen MoritzTodd S Woodward
Jul 8, 2014·Journal of Behavior Therapy and Experimental Psychiatry·Daniel FreemanNicole Evans
Jul 10, 2014·Social Psychiatry and Psychiatric Epidemiology·Daniel Freeman, Philippa Garety
Jul 11, 2014·Journal of Behavior Therapy and Experimental Psychiatry·Elena MarcusSuzanne Jolley

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Citations

Jan 17, 2016·The Lancet. Psychiatry·Elizabeth KuipersEmmanuelle Peters
Aug 10, 2016·Journal of Behavior Therapy and Experimental Psychiatry·Steffen MoritzChristina Andreou
Aug 17, 2016·Journal of Behavior Therapy and Experimental Psychiatry·Łukasz GawędaRyan P Balzan
Sep 7, 2016·Schizophrenia Research·Steffen MoritzMona Dietrichkeit
Aug 1, 2018·Journal of Cognitive Psychotherapy·Devvarta Kumar, Ganesan Venkatasubramanian
Apr 12, 2017·Schizophrenia Bulletin·Paul Bebbington, Daniel Freeman
Oct 22, 2020·Development and Psychopathology·Aino SaarinenLiisa Keltikangas-Järvinen
Jul 23, 2020·Revista de psiquiatrí́a y salud mental·Maria Jose EscandellEmma Casas-Anguera
Jan 27, 2019·Psychiatry Research·Martyna KrężołekŁukasz Gawęda

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Clinical Trials Mentioned

ISRCTN59501939

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STATA

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