Thiocarbonyl-enabled ferrocene C-H nitrogenation by cobalt(III) catalysis: thermal and mechanochemical

Beilstein Journal of Organic Chemistry
Santhivardhana Reddy YetraLutz Ackermann

Abstract

Versatile C-H amidations of synthetically useful ferrocenes were accomplished by weakly-coordinating thiocarbonyl-assisted cobalt catalysis. Thus, carboxylates enabled ferrocene C-H nitrogenations with dioxazolones, featuring ample substrate scope and robust functional group tolerance. Mechanistic studies provided strong support for a facile organometallic C-H activation manifold.

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Citations

May 12, 2019·Angewandte Chemie·Joachim LoupLutz Ackermann
Oct 9, 2020·Angewandte Chemie·Shengjun NiLukasz T Pilarski
Mar 14, 2021·Organic Letters·Zhuo-Zhuo ZhangBing-Feng Shi
May 26, 2021·Organic Letters·Kazuya KanemotoShin-Ichi Fukuzawa
Jan 27, 2019·Organic Letters·Dan-Ying HuangBing-Feng Shi
Mar 25, 2020·Organic Letters·Sourav Sekhar Bera, Modhu Sudan Maji
Nov 25, 2021·Organic & Biomolecular Chemistry·Pengpeng GaoQing-Zhong Zheng
Jan 6, 2022·Organic & Biomolecular Chemistry·Hui XieFan Yang

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Methods Mentioned

BETA
amidation
NMR

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