Thiocyanation and 2-Amino-1,3-thiazole Formation in Water Using Recoverable and Reusable Glycosylated Resorcin[4]arene Cavitands.

The Journal of Organic Chemistry
Ali A Husain, Kirpal S Bisht

Abstract

A family of three spatially directional resorcin[4]arene cavitand glycoconjugates (RCGs) have been applied as efficient recoverable and reusable inverse phase transfer catalysts for eco- and environmentally friendly thiocyanation and 2-amino-1,3-thiazole formation reactions in water. The results show that RCGs (1 mol %) were capable of hosting and catalyzing various water-insoluble bromo/thiocyanato substrates in water without the use of any co-organic solvents. The recoverability and reusability of RCG catalytic systems, that is, RCG1 and RCG3, were also examined upon a simple extraction of the desired products using DCM or ethyl acetate, followed by subjecting the recovered aqueous solution containing the RCG catalysts to the next reaction cycles.

References

Jun 6, 2000·American Journal of Respiratory Cell and Molecular Biology·C GersonG E Conner
Oct 25, 2001·The Journal of Organic Chemistry·Patrick C. KearneyJohn A. Flygare
Apr 2, 2002·The Journal of Organic Chemistry·Belén BataneroAvelino Martín
Sep 9, 2008·Bioorganic & Medicinal Chemistry Letters·Robert G GentlesDavid G Harden
May 8, 2009·Bioorganic & Medicinal Chemistry·Sabrina HengEvan R Kantrowitz
Jan 21, 2011·Journal of Medicinal Chemistry·Alejandra Gallardo-GodoyAdam R Renslo
May 3, 2015·European Journal of Medicinal Chemistry·Adile AyatiAlireza Foroumadi
Jan 16, 2016·European Journal of Medicinal Chemistry·Debasis DasMoumita Bairagi
Mar 5, 2016·Chemistry : a European Journal·Ali A HusainKirpal S Bisht
May 7, 2016·Current Topics in Medicinal Chemistry·Mahesh T ChhabriaPathik S Brahmkshatriya

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Citations

Nov 17, 2021·The Journal of Organic Chemistry·Jin-Cheng LiHua-Yue Wu

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