Thiopentone pretreatment for propofol injection pain in ambulatory patients

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
R D HaugenP M Merrick

Abstract

This study investigated propofol injection pain in patients undergoing ambulatory anaesthesia. In a randomized, double-blind trial, 90 women were allocated to receive one of three treatments prior to induction of anaesthesia with propofol. Patients in Group C received 2 ml normal saline, Group L, 2 ml, lidocaine 2% (40 mg) and Group T, 2 ml thiopentone 2.5% (50 mg). Venous discomfort was assessed with a visual analogue scale (VAS) 5-15 sec after commencing propofol administration using an infusion pump (rate 1000 micrograms.kg-1.min-1). Loss of consciousness occurred in 60-90 sec. Visual analogue scores (mean +/- SD) during induction were lower in Groups L (3.3 +/- 2.5) and T (4.1 +/- 2.7) than in Group C (5.6 +/- 2.3); P = 0.0031. The incidence of venous discomfort was lower in Group L (76.6%; P < 0.05) than in Group C (100%) but not different from Group T (90%). The VAS scores for recall of pain in the recovery room were correlated with the VAS scores during induction (r = 0.7045; P < 0.0001). Recovery room discharge times were similar: C (75.9 +/- 19.4 min); L 73.6 +/- 21.6 min); T (77.1 +/- 18.9 min). Assessing their overall satisfaction, 89.7% would choose propofol anaesthesia again. We conclude that lidocaine reduces the ...Continue Reading

References

Sep 1, 1992·Journal of Clinical Anesthesia·B K Philip
Feb 1, 1992·Anesthesia and Analgesia·S Y KingP J Pryor
Feb 1, 1991·British Journal of Anaesthesia·E Anker-MøllerP Bjerring
Sep 1, 1991·British Journal of Anaesthesia·W Klement, J O Arndt
Mar 1, 1991·British Journal of Anaesthesia·G GehanJ L Pourriat
Jun 1, 1990·Anaesthesia·R A JohnsonA Vohra
Jun 1, 1990·Anaesthesia·A McCrirrick, S Hunter
Mar 1, 1990·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·J H HelmersW W Zuurmond
Feb 1, 1989·British Journal of Anaesthesia·D N StokesP Hutton
Jan 1, 1985·Anaesthesia·J BrookerM Stafford
Aug 1, 1985·Acta Anaesthesiologica Scandinavica·M HynynenT Tammisto

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Citations

Dec 13, 2002·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Rachel C PollardCarolyne J Montgomery
Oct 4, 2006·Current Opinion in Anaesthesiology·P H Tonner, J Scholz
Aug 1, 1997·Anesthesia and Analgesia·R W PetersM R Gold
Mar 29, 2000·Anesthesia and Analgesia·P Picard, M R Tramèr
Feb 26, 2004·Anesthesia and Analgesia·Anil AgarwalUttam Singh
May 16, 2014·Iranian Red Crescent Medical Journal·Mohammad GharaviMohsen Akhondi
Jan 1, 2010·Anesthesia, Essays and Researches·Yasser Mohamed Amr, Sabry M Amin
Jun 11, 1998·Journal of Pharmaceutical Sciences·G A BrazeauP Gupta
Feb 19, 2016·The Cochrane Database of Systematic Reviews·Pramote EuasobhonPisake Lumbiganon
Feb 18, 2005·Acta Anaesthesiologica Scandinavica·E Liljeroth, J Akeson
Aug 12, 1998·European Journal of Anaesthesiology·H G PawG T Rich
May 16, 2014·Iranian Red Crescent Medical Journal·Mohammad AlipourMasoomeh Alipour
Jul 27, 2001·Acta Anaesthesiologica Scandinavica·E LiljerothJ Akeson
Mar 23, 2001·Anaesthesia and Intensive Care·K S YeoM K Onsiong
Jul 11, 1998·Anaesthesia·C H Tan, M K Onsiong

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