Third wave of African swine fever infection in Armenia: Virus demonstrates the reduction of pathogenicity

Veterinary World
M A SargsyanZ A Karalyan

Abstract

First cases of clinically uncommon African swine fever (ASF), caused by virus genotype II are described in this article. These cases occurred in Armenia, Tavush region, Dilijan municipality in 2011. The aim of this study was to identify and describe the new pathogenic forms of ASF in Armenia. The isolation and identification of ASF virus (ASFV) were carried out using conventional techniques. Clinical signs of infection were recorded daily. Gross anatomical pathology characteristics were observed during routine postmortem examinations. Blood and serum were obtained by puncture of the jugular vein using a vacutainer system. The presence of ASFV DNA in the spleens was confirmed by polymerase chain reaction. Sequenced sections of p72 showed phylogenetic identity to genotype 2. The pathology exhibits unusual manifestations of the main disease. The unusual form of ASF demonstrates characteristics of a subacute form of the disease, with the possibility of conversion to a chronic form. Decreased lethality, low level of hemorrhages, and absence of severe pancytopenia in smears from spleen, lymph nodes, and blood are common features of the new form of ASF. Unlike severe thrombocytopenia in the typical ASF, the unusual form exhibited mode...Continue Reading

References

Feb 1, 1988·Virus Research·I C PanM Shimizu
Sep 14, 1996·The Veterinary Record·F RodríguezA Jover
Oct 17, 2009·Journal of the South African Veterinary Association·M L Penrith, W Vosloo
Apr 8, 2011·Emerging Infectious Diseases·David A G ChapmanLinda K Dixon
Nov 6, 2012·Virus Research·S CostardD U Pfeiffer
Sep 23, 2014·Veterinary Microbiology·Hovakim ZakaryanZaven Karalyan
Dec 3, 2014·Journal of Comparative Pathology·J M Sánchez-VizcaínoL Carrasco
Aug 19, 2016·Veterinary World·Z A KaralyanE M Karalova
Jun 10, 2017·PloS One·Esther Andrea KukielkaDaniel Beltrán-Alcrudo

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Citations

Mar 23, 2019·Emerging Microbes & Infections·Dongming ZhaoZhigao Bu
Apr 17, 2020·Frontiers in Veterinary Science·Marta Martínez-AvilésAna De La Torre
Sep 27, 2020·Transboundary and Emerging Diseases·Uda Zahli IzzatiRyoji Yamaguchi
Jun 5, 2021·Veterinary World·Hranush ArzumanyanZaven Karalyan

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Methods Mentioned

BETA
biopsies
PCRs
PCR

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