Thirty-Day Outcomes After Craniotomy for Primary Malignant Brain Tumors: A National Surgical Quality Improvement Program Analysis

Neurosurgery
Joeky T SendersTimothy R Smith

Abstract

Despite improved perioperative management, the rate of postoperative morbidity and mortality after brain tumor resection remains considerably high. To assess the rates, causes, timing, and predictors of major complication, extended length of stay (>10 d), reoperation, readmission, and death within 30 d after craniotomy for primary malignant brain tumors. Patients were extracted from the National Surgical Quality Improvement Program registry (2005-2015) and analyzed using multivariable logistic regression. A total of 7376 patients were identified, of which 948 (12.9%) experienced a major complication. The most common major complications were reoperation (5.1%), venous thromboembolism (3.5%), and death (2.6%). Furthermore, 15.6% stayed longer than 10 d, and 11.5% were readmitted within 30 d after surgery. The most common reasons for reoperation and readmission were intracranial hemorrhage (18.5%) and wound-related complications (11.9%), respectively. Multivariable analysis identified older age, higher body mass index, higher American Society of Anesthesiologists (ASA) classification, dependent functional status, elevated preoperative white blood cell count (white blood cell count [WBC], >12 000 cells/mm3), and longer operative ti...Continue Reading

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Citations

Jan 13, 2019·Acta neurochirurgica·Stephanie SchipmannWalter Stummer
Jul 4, 2020·Acta neurochirurgica·Maria ZetterlingElisabeth Ronne Engström
Nov 28, 2020·Annals of Oncology : Official Journal of the European Society for Medical Oncology·P RothUNKNOWN ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Dec 22, 2020·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Catherine M GarciaRobert J Weil
Nov 7, 2021·World Neurosurgery·Eagan J PetersDemitre Serletis

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