Thirty-Day Outcomes following Pediatric Bone and Soft Tissue Sarcoma Surgery: A NSQIP Pediatrics Analysis

Sarcoma
Kathryn E GallawayAlexandra K Callan

Abstract

Pediatric bone and soft tissue sarcomas are rare; therefore, national registries are essential tools for orthopedic oncology research. Past studies provide excellent data on long-term prognosis and survival trends but fail to examine treatment-specific morbidity. The aim of this study is to use a national registry to describe patient demographics, comorbidities, and adverse events in the first thirty days following surgical management of pediatric bone and soft tissue sarcomas. A retrospective review of patients in the American College of Surgeons National Surgical Quality Improvement Program-Pediatrics database (NSQIP-P) was performed. The cohort was partitioned by tumor origin (bone versus soft tissue) and tumor location (axial versus appendicular). One-hundred ninety-two patients were identified. Bone sarcomas were more common (71.9%) and predominately appendicular (62.3%), while soft tissue sarcomas were predominately axial (77.8%). The overall complication rate was 8.9%. The most frequent etiologies were wound dehiscence (3.6%) and infectious complications such as surgical site infections (2.6%), pneumonia (1.6%), urinary tract infections (1.6%), and C. diff colitis (1.0%). Twenty-four percent of patients experienced bleed...Continue Reading

References

Oct 29, 2008·Journal of the American College of Surgeons·John D BirkmeyerBruce Lee Hall
May 13, 2011·Clinical Orthopaedics and Related Research·Xin LiRichard D Lackman
May 9, 2012·Mayo Clinic Proceedings·Carola A S ArndtNadia N Laack
Mar 25, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·T PeelP Choong
May 2, 2015·Journal of Pediatric Orthopedics·Shobhit V MinhasNorman Y Otsuka
Jul 16, 2015·Pediatric Blood & Cancer·Thalia WongSteven G DuBois
Aug 26, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nathalie GasparOdile Oberlin
Sep 28, 2015·The Spine Journal : Official Journal of the North American Spine Society·Andrew J SchoenfeldMitchel B Harris
Nov 13, 2015·Journal of Pediatric Orthopedics·Bryce A BasquesJonathan N Grauer
Nov 14, 2015·World Journal of Clinical Pediatrics·Surasak Sangkhathat
Jan 13, 2016·Journal of Pediatric Orthopedics·Wanlim KimHan-Soo Kim
Apr 30, 2016·Journal of Surgical Oncology·Santiago A Lozano-CalderónMark C Gebhardt
May 21, 2016·Journal of Pediatric Surgery·Stephanie ThibaudeauRobert B Carrigan
Jun 10, 2016·Journal of Pediatric Orthopedics·Brandon A SherrodShawn R Gilbert
Jan 7, 2017·The Annals of Otology, Rhinology, and Laryngology·Mark A EllisEric J Lentsch
Jul 25, 2017·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Robert J LeeRussell E Christensen
Aug 15, 2017·International Journal of Pediatric Otorhinolaryngology·Jacob S BradyRichard Chan Woo Park
Mar 15, 2018·Expert Review of Anticancer Therapy·Wen-Tong ZhangSan-Gang Wu
Apr 28, 2018·Journal of Neurosurgery. Pediatrics·K Aaron ShawJoshua S Murphy
Jan 28, 2019·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Sigbjørn SmelandNeyssa Marina
Feb 17, 2019·Hand : Official Journal of the American Association for Hand Surgery·Fouad ChouairiMichael Alperovich

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Citations

Sep 22, 2021·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Katharina GeißlerOrlando Guntinas-Lichius

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