Thirty-six-month outcomes of drug-eluting balloon angioplasty in the infrapopliteal arteries

Vascular
Berkan OzpakMustafa Cagdas Cayir

Abstract

Objectives To evaluate 36-month outcomes of drug-eluting balloons in infrapopliteal (=below-the-knee) arterial segments, we made a prospective registry enrolling patients (Rutherford class 2 to 5, ankle-brachial index 0.4-0.7) who were revascularized with drug-eluting balloon from August 2011 to December 2014. Methods Three hundred and seven infrapopliteal arteries were revascularized only with drug-eluting balloon. Endpoints included target lesion revascularization, primary patency rate, and changes in ankle-brachial index and Rutherford class. Results Both ankle-brachial index improvement and Rutherford reduction were statistically significant (p < 0.001). At 36 months control, ankle-brachial index improvement was 59.3% (p = 0.032). The clinically driven target lesion revascularization rate was 28% at 36 months. Limb salvage was accomplished in 73.6% of the critical limb ischemia cases, and complete wound healing was detected in 67.8% of cases with Rutherford category 5. Overall, the 1-year primary patency rate was 32.5%. Conclusions Drug-eluting balloons have shown successful performance in infrapopliteal arteries in mid-term, and evidence regarding clinical effectiveness and safety supports drug-eluting balloon angioplasty ...Continue Reading

References

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Citations

Jun 9, 2020·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Stefanos GiannopoulosEhrin J Armstrong
Jan 1, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Jetty IpemaÇağdaş Ünlü
Nov 3, 2020·The International Journal of Angiology : Official Publication of the International College of Angiology, Inc·Gautam M AnandGary Giangola

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Methods Mentioned

BETA
percutaneous transluminal angioplasty

Software Mentioned

SPSS

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