Thoracic and abdominal organ uptake of 2-deoxy-2-[18F]fluoro-D-glucose (18FDG) with positron emission tomography in the normal dog

Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Amy K LeBancGregory B Daniel

Abstract

Positron emission tomography (PET) has found widespread application for staging and monitoring neoplastic diseases in humans. PET is becoming more available in veterinary medicine, therefore biodistribution of 2-deoxy-2-[18F]fluoro-D-glucose (18FDG) in normal dogs is needed for lesion interpretation in disease states. A large field-of-view (FOV) PET scanner with a 70 cm bore diameter and a 53-cm FOV was used in this study to acquire dynamic 18FDG uptake data from parenchymal organs in seven normal dogs. A 2-h, dynamic list-mode acquisition was initiated simultaneously with intravenous 18FDG injection. Regions of interest (ROIs) were manually drawn over liver, spleen, left and right renal cortices, left ventricular free wall, and thymus. Standardized uptake values (SUVs) of these organs were calculated for 24 5-min frames over the 2-h acquisition. This SUV data from parenchymal organs of normal dogs compares favorably with those of normal humans and will be used in ongoing canine studies using PET to evaluate various diseases.

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Citations

Feb 27, 2013·American Journal of Veterinary Research·Michael P JonesAmy K LeBlanc
May 29, 2014·American Journal of Veterinary Research·Lindsay M WilliamsAmy K LeBlanc
Dec 10, 2013·Seminars in Nuclear Medicine·Amy K LeBlanc, Kathelijne Peremans
Apr 30, 2009·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Amy K LeBlancGregory B Daniel
Mar 1, 2012·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Amy K LeblancFederica Morandi
Dec 17, 2010·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Min-Su LeeKi-Dong Eom
Mar 8, 2013·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Joshua A RoweAmy K LeBlanc
May 11, 2011·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Marcy J SouzaGregory B Daniel
Jan 29, 2014·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Elissa RandallSusan Kraft
Oct 10, 2013·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Amy K LeBlanc, Federica Morandi
Apr 14, 2016·The Veterinary Clinics of North America. Small Animal Practice·Elissa K Randall
Dec 21, 2013·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Tarja S JokinenLiisa Metsähonkala
Aug 25, 2009·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Amy K LeBlancGregory B Daniel
Jun 19, 2012·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Nicole E MartinezThomas E Johnson
Sep 20, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Megan GrobmanCarol Reinero
Mar 11, 2011·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Anders E HansenAnnemarie T Kristensen
Apr 21, 2010·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Ah Ra LeeKidong Eom
Jun 21, 2021·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Sabrina WilsonLarry Galuppo

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