Abstract
Prognosis with esophageal carcinoma above the carina is generally thought to be the worst without any conclusive demonstration. Clinicopathologic features of 101 patients with thoracic esophageal carcinoma above the carina (AC group) were compared with those of 665 patients with a tumor below this level (BC group). The number of T4 tumor was significantly larger in the AC group (P < 0.001). Survival curve for all patients in the AC group was significantly worse than the BC group (P < 0.001). Survival in patients who underwent any treatment other than esophagectomy was equally bad in the two groups. However, survival in patients undergoing esophagectomy was similar in the two groups (P = 0.64), with the cumulative 5-year survival rates of 44.5% and 43.1%, respectively. Even in patients with metastatic disease in the lymph nodes, the cumulative 5-year survival rates after radical esophagectomy were similar. The prognosis of patients in the AC group is generally worse than the BC group because of the close anatomical relationship with the tracheobronchial tree. However, radical esophagectomy is recommended for patients at stages less advanced than T4.
References
Jun 1, 1976·The Japanese Journal of Surgery· Japanese Society for Esophageal Diseases
Sep 15, 1992·Cancer·H KatoM Itabashi
Dec 24, 1990·Brain Research·B W Newton
Aug 1, 1991·Journal of Surgical Oncology·K WelvaartJ Hermans
Jan 1, 1991·Oncology·K IsonoK Nakayama
Oct 1, 1991·Journal of Surgical Oncology·H KatoT Hirota
Jun 1, 1991·The Annals of Thoracic Surgery·H KatoT Iizuka
Aug 1, 1990·The British Journal of Surgery·J M MüllerH Pichlmaier
Mar 1, 1994·The Annals of Thoracic Surgery·H J FahnK Y Chien
Dec 1, 1958·Journal of Chronic Diseases·S J CUTLER, F EDERER
Jun 1, 1965·Biometrika·E A GEHAN
Citations
Jul 21, 2000·Annals of Surgery·N AndoM Kitajima
Sep 23, 2003·Annals of Surgery·Simon LawJohn Wong
Oct 20, 2004·Annals of Surgery·Simon LawJohn Wong
May 4, 2012·The Annals of Thoracic Surgery·Hao-Xian YangJian-Hua Fu
Jun 28, 2011·The Annals of Thoracic Surgery·Hee-Jin JangJae Ill Zo
May 16, 2006·Thoracic Surgery Clinics·B Zane Atkins, Thomas A D'Amico
Mar 2, 2005·Annales de chirurgie·G PiessenJ P Triboulet
Oct 18, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C G ManshandenH Obertop
May 18, 2004·Surgical Oncology·Alan D L SihoeAnthony P C Yim
Oct 26, 2013·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·S TakenoK Kawahara
Jun 26, 2014·Journal of the Renin-angiotensin-aldosterone System : JRAAS·Yen-Hao ChenShau-Hsuan Li
Dec 6, 2017·BMC Cancer·Kazuki KanoTakashi Ogata
Oct 13, 1999·Journal of Surgical Oncology·M TachibanaN Nagasue
Jul 6, 2005·The British Journal of Surgery·H IgakiT Shimoda
Feb 18, 2006·Annals of Surgical Oncology·Lorenzo E FerriJohn Wong
May 12, 2018·Annals of Surgical Oncology·Kazuki KanoTakashi Ogata
Aug 6, 2000·Tropical Medicine & International Health : TM & IH·J VisschedijkP Klatser
Jan 16, 2014·Indian Journal of Surgical Oncology·Sanjay Sharma
Sep 24, 2020·Journal of Bronchology & Interventional Pulmonology·Ajmal KhanAlok Nath