PMID: 7083935Jul 1, 1982Paper

Thoracoscopic lung biopsy. Experimental and clinical preliminary study

Chest
C BoutinF Rey

Abstract

We have investigated thoracoscopic lung biopsy (TLB) as an alternative to surgical biopsy. TLB was performed under mild general anesthesia, with two openings: one for the telescope, and one for a 5 mm in diameter biopsy forceps connected to diathermocoagulating device. TLB was first tested on 14 dogs (22 TLB) and then on 75 subjects (77 TLB): 35 patients with pleural diseases and 40 patients with undiagnosed lung diseases despite previous investigations including transbronchial biopsy. TLB yielded a high rate of adequate samples (up to 5 x 5 x 5 mm) in both experimental (95 percent) and clinical series (96 percent). Overall sensitivity equalled 923 percent, ranging from 70 percent in peripheral localized lesions to 100 percent in diffuse lung diseases. The mean period of systematic drainage was 3.4 +/- 0.3 days, and the main complications we encountered were one transient blood-streaked sputum specimen and eight localized pneumothoraces during drainage. TLB is indicated when other medical procedures have failed, and has thus proved, in this series, to be as sensitive as surgical biopsy with less morbidity and no mortality.

Citations

Dec 1, 1994·Annals of Surgery·Larry R Kaiser
Jan 1, 1992·The Australian and New Zealand Journal of Surgery·B G O'RiordanD R Fletcher
Dec 28, 2006·Respiration; International Review of Thoracic Diseases·Florin V Moisiuc, Henri G Colt
Jul 1, 1992·Chest·P Mathur, W J Martin
Nov 1, 1993·Chest·J P Janssen, P E Postmus
Dec 19, 2012·The Annals of Thoracic Surgery·Eugenio PompeoCesare Saltini
Aug 18, 2009·The Veterinary Clinics of North America. Small Animal Practice·Chad Schmiedt
Sep 1, 1987·American Journal of Surgery·V Rusch, C Mountain
Jun 27, 2020·Expert Review of Respiratory Medicine·Faisal ShaikhFabien Maldonado
Mar 1, 1994·Annals of Surgical Oncology·V RuschR Ginsberg
Sep 10, 2015·Cancer Control : Journal of the Moffitt Cancer Center·Frank O Velez-CubianEric M Toloza
Mar 22, 2001·Annals of Surgical Oncology·K ParekhR Ginsberg

Related Concepts

Biopsy
Needle Biopsy Procedure
Canis familiaris
Lung
Lung Diseases
Surgical Procedures, Thoracoscopic

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.