Thought Chart: tracking the thought with manifold learning during emotion regulation

Brain Informatics
Mengqi XingAlex Leow

Abstract

The Nash embedding theorem demonstrates that any compact manifold can be isometrically embedded in a Euclidean space. Assuming the complex brain states form a high-dimensional manifold in a topological space, we propose a manifold learning framework, termed Thought Chart, to reconstruct and visualize the manifold in a low-dimensional space. Furthermore, it serves as a data-driven approach to discover the underlying dynamics when the brain is engaged in a series of emotion and cognitive regulation tasks. EEG-based temporal dynamic functional connectomes are created based on 20 psychiatrically healthy participants' EEG recordings during resting state and an emotion regulation task. Graph dissimilarity space embedding was applied to all the dynamic EEG connectomes. In order to visualize the learned manifold in a lower dimensional space, local neighborhood information is reconstructed via k-nearest neighbor-based nonlinear dimensionality reduction (NDR) and epsilon distance-based NDR. We showed that two neighborhood constructing approaches of NDR embed the manifold in a two-dimensional space, which we named Thought Chart. In Thought Chart, different task conditions represent distinct trajectories. Properties such as the distributio...Continue Reading

References

Dec 23, 2000·Science·J B TenenbaumJ C Langford
Dec 23, 2000·Science·S T Roweis, L K Saul
Apr 6, 2007·Journal of Neural Engineering·F LotteB Arnaldi
Oct 3, 2008·Human Brain Mapping·Zhenyu ZhouYijun Liu
Nov 4, 2009·Psychological Science·Russell A PoldrackStephen José Hanson
Jan 19, 2011·International Journal of Neural Systems·Raúl Cruz-Barbosa, Alfredo Vellido
Jul 27, 2011·IEEE Transactions on Medical Imaging·P AljabarD Rueckert
Sep 29, 2011·Human Brain Mapping·Andreas KeilPeter J Lang
Jul 10, 2012·Cognitive, Affective & Behavioral Neuroscience·Muhammad A ParvazGreg Hajcak
Jan 5, 2013·Medical Image Computing and Computer-assisted Intervention : MICCAI·Dong Hye YeKilian M Pohl
Nov 19, 2015·Human Brain Mapping·Matthew A AlbrechtMathew T Martin-Iverson
Jun 9, 2016·Cognitive Neurodynamics·Arturo Tozzi, James F Peters

❮ Previous
Next ❯

Methods Mentioned

BETA
PCA

Software Mentioned

Fieldtrip
Thought Chart
isomap
MATLAB

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

IEEE Transactions on Pattern Analysis and Machine Intelligence
Kevin M CarterAlfred O Hero
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
A M Alvarez-MezaG Castellanos-Dominguez
IEEE Transactions on Pattern Analysis and Machine Intelligence
Rui LiStan Sclaroff
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
P GifaniM Ghanbari
© 2022 Meta ULC. All rights reserved