Thought suppression as a mediator of the association between depressed mood and prescription opioid craving among chronic pain patients

Journal of Behavioral Medicine
Eric L GarlandMatthew O Howard

Abstract

Emerging research suggests that prescription opioid craving is associated with negative mood and depression, but less is known about cognitive factors linking depressive symptoms to opioid craving among adults with chronic pain. The present cross-sectional study examined thought suppression as a mediator of the relation between depression and prescription opioid craving in a sample of chronic pain patients receiving long-term opioid pharmacotherapy. Data were obtained from 115 chronic pain patients recruited from primary care, pain, and neurology clinics who had taken prescription opioids daily or nearly every day for ≥90 days prior to assessment. In this sample, 60 % of participants met DSM-IV criteria for current major depressive disorder. Depressed mood (r = .36, p < .001) and thought suppression (r = .33, p < .001) were significantly correlated with opioid craving. Multivariate path analyses with bootstrapping indicated the presence of a significant indirect effect of thought suppression on the association between depressed mood and opioid craving (indirect effect = .09, 95 % CI .01, .20). Sensitivity analyses showed a similar indirect effect of suppression linking major depressive disorder diagnosis and opioid craving. Att...Continue Reading

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Citations

May 20, 2017·International Journal of Behavioral Medicine·Kerstin KonietznyMonika Ilona Hasenbring
Dec 19, 2017·Psychopharmacology·Mark A WareJoel Singer
Apr 19, 2018·Physical Therapy·Sarah WengerJoke Bradt
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Mar 7, 2021·Translational Research : the Journal of Laboratory and Clinical Medicine·Marc O MartelRobert R Edwards
Oct 9, 2020·The Journal of Pain : Official Journal of the American Pain Society·Yun ShenAmie J Goodin
Apr 4, 2021·International Journal of Environmental Research and Public Health·Rosa EsteveCarmen Ramírez-Maestre

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