Thraustochytrid Marine Protists: production of PUFAs and Other Emerging Technologies.

Marine Biotechnology
Seshagiri Raghukumar

Abstract

Thraustochytrids, the heterotrophic, marine, straminipilan protists, are now established candidates for commercial production of the omega-3 polyunsaturated fatty acid (omega-3 PUFA), docosahexaenoic acid (DHA), that is important in human health and aquaculture. Extensive screening of cultures from a variety of habitats has yielded strains that produce at least 50% of their biomass as lipids, and DHA comprising at least 25% of the total fatty acids, with a yield of at least 5 g L(-1). Most of the lipids occur as triacylglycerols and a lesser amount as phospholipids. Numerous studies have been carried out on salinity, pH, temperature, and media optimization for DHA production. Commercial production is based on a fed batch method, using high C/N ratio that favors lipid accumulation. Schizochytrium DHA is now commercially available as nutritional supplements for adults and as feeds to enhance DHA levels in larvae of aquaculture animals. Thraustochytrids are emerging as a potential source of other PUFAs such as arachidonic acid and oils with a suite of PUFA profiles that can have specific uses. They are potential sources of asataxanthin and carotenoid pigments, as well as other lipids. Genes of the conventional fatty acid synthesis...Continue Reading

References

Jan 1, 1973·Annual Review of Microbiology·S Goldstein
Jul 1, 1994·Journal of Industrial Microbiology·Z Y Li, O P Ward
Jan 1, 1997·Advances in Applied Microbiology·A Singh, O P Ward
Feb 21, 1998·Trends in Biotechnology·I W Sutherland
Dec 29, 1999·Marine Biotechnology·T E LewisT A McMeekin
Jan 5, 2000·The American Journal of Clinical Nutrition·W E Connor
Sep 10, 2002·Trends in Biochemical Sciences·James G WallisJohn Browse
May 17, 2003·Applied Microbiology and Biotechnology·Y KumonT Nakahara
Oct 29, 2003·Chemistry and Physics of Lipids·William Stillwell, Stephen R Wassall
Jan 24, 2004·Applied Microbiology and Biotechnology·L Sijtsma, M E de Swaaf
Mar 5, 2004·Journal of Agricultural and Food Chemistry·Yue JiangFeng Chen
Apr 12, 2005·Applied Microbiology and Biotechnology·Yasuyuki KumonToro Nakahara
Apr 20, 2005·Letters in Applied Microbiology·S Patnayak, A Sree
May 24, 2005·Marine Biotechnology·Ruchi JainN B Bhosle
Oct 1, 2005·Molecular Biology of the Cell·Ruben M MarkosyanGrigory B Melikyan
Dec 29, 2005·Marine Biotechnology·Yasuyuki KumonToro Nakahara
Jun 10, 2006·Marine Biotechnology·Eiko MoritaTetsuko Noguchi
Dec 21, 2006·Journal of Agricultural and Food Chemistry·Roberto E ArmentaColin J Barrow
Jan 11, 2007·Bioscience, Biotechnology, and Biochemistry·Masahiro HayashiYoshihisa Nakano
Mar 27, 2007·Journal of Agricultural and Food Chemistry·King-Wai FanFeng Chen
Jan 1, 1996·World Journal of Microbiology & Biotechnology·A SinghO P Ward

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Citations

Jul 1, 2009·Applied Microbiology and Biotechnology·Eiji SakuradaniSakayu Shimizu
Jul 2, 2011·Applied Microbiology and Biotechnology·Inna Khozin-GoldbergZvi Cohen
Apr 10, 2013·Marine Biotechnology·Lana ShabalaSergey Shabala
Aug 31, 2013·Journal of Industrial Microbiology & Biotechnology·Adarsha GuptaColin J Barrow
Jan 25, 2013·Marine Drugs·Carla C C R de Carvalho, Maria José Caramujo
Jun 29, 2013·Marine Drugs·Dulce Alves MartinsKhalid M Abu-Salah
May 9, 2014·Applied Microbiology and Biotechnology·Purnima SinghGuangyi Wang
May 4, 2013·Journal of Bioscience and Bioengineering·Naoki NaganoMasahiro Hayashi
Dec 15, 2015·Bioprocess and Biosystems Engineering·Wei ChenLongjiang Yu
Mar 19, 2013·Prostaglandins & Other Lipid Mediators·Michail I GladyshevOlesia N Makhutova
Nov 18, 2015·Applied Microbiology and Biotechnology·Joshua LowreyMarianne S Brooks
Mar 24, 2016·Applied Microbiology and Biotechnology·Joshua LowreyRoberto E Armenta
Mar 20, 2010·The Journal of Eukaryotic Microbiology·Nachshon SiboniAriel Kushmaro
Aug 20, 2015·Applied Microbiology and Biotechnology·Yunxuan Xie, Guangyi Wang
Apr 5, 2016·Applied Microbiology and Biotechnology·Inga Marie AasenTrond E Ellingsen
Mar 13, 2012·Biotechnology Advances·Adarsha GuptaMunish Puri
Nov 25, 2011·Enzyme and Microbial Technology·Spencer D ScottAndrew W Norman
May 7, 2011·Phytochemistry·Kim Jye Lee ChangPeter D Nichols
Nov 26, 2014·Journal of Agricultural and Food Chemistry·Yung Lee SuenFeng Chen
May 9, 2016·Journal of Industrial Microbiology & Biotechnology·Joshua LowreyMarianne S Brooks
Oct 12, 2017·Preparative Biochemistry & Biotechnology·Priyanka V Shirodkar, Usha Devi Muraleedharan
Aug 11, 2017·Bioscience, Biotechnology, and Biochemistry·Masato OtagiriShunji Takahashi
Feb 7, 2017·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Valcenir Júnior Mendes FurlanNarcisa Maria Bandarra

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