Three Cases of COVID-19 Pneumonia in Female Patients in Italy Who Had Pulmonary Fibrosis on Follow-Up Lung Computed Tomography Imaging

The American Journal of Case Reports
Giovanna PicchiAlessandro Grimaldi

Abstract

BACKGROUND Since December 2019, an outbreak caused by a novel coronavirus infection (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) occurred in Wuhan, China, and it rapidly spread all over the world. The clinical spectrum of coronavirus disease 2019 (COVID-19) is wide, with acute respiratory distress syndrome (ARDS) occurring in 15% of patients affected, requiring high oxygen support. Currently, there is no clearly effective antiviral therapy. Steroids and immunomodulators are under investigation for potential activity. Little is known about middle and long-term sequelae on respiratory function. According to some authors, COVID-19 could cause pulmonary fibrosis. We report 3 cases of pulmonary fibrosis detected on follow-up computed tomography (CT) imaging in 3 female patients who recovered from COVID-19 pneumonia in Italy (L'Aquila, Abruzzo). CASE REPORT All patients were female and had no significant previous respiratory disease or history of smoke exposure, and none had received high-flow oxygen support during treatment of the disease. In all cases, late onset of mild dyspnea, slow and incomplete respiratory recovery, and early evidence of fibrous signs on chest CT scan were characteristic of the clinical course...Continue Reading

Citations

Feb 15, 2021·Pulmonology·M PolastriF Tagariello
Apr 28, 2021·Expert Review of Respiratory Medicine·Suzana Erico TanniBruno Guedes Baldi
Apr 20, 2021·Curēus·Bilal MalikAbhijeet Ghatol
Apr 29, 2021·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·Gianluca E M BoariDamiano Rizzoni
Feb 19, 2021·European Journal of Physical and Rehabilitation Medicine·Alessandro de SireUNKNOWN International Multiprofessional Steering Committee of Cochrane Rehabilitation REH-COVER Action

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