Three cases of pancreatic serous cystadenoma and endocrine tumour.

Journal of Clinical Pathology
Stella BlandamuraVito Ninfo

Abstract

To report three cases of serous cystadenoma and endocrine tumour in the same pancreas, to review the literature and to evaluate the clinicopathological features of the tumours. Three women (71, 57 and 31 years old) were admitted to hospital, two for diseases unrelated to the pancreas and the third for increasing obstructive jaundice in von Hippel-Lindau disease. Preoperative examination showed two distinct lesions in the first patient and only cystic lesions in the other two. Histological examination of the pancreas showed one serous oligocystic adenoma associated with a benign, well-differentiated endocrine tumour, one serous oligocystic adenoma associated with an endocrine microadenoma, and a von Hippel-Lindau-related cystic neoplasm with a well-differentiated endocrine carcinoma. Serous cystadenoma associated with endocrine tumour shows some clinicopathological differences with respect to the two tumours considered separately, and with respect to von Hippel-Lindau-related cases, although there is no convincing evidence at present to justify considering this association as a separate entity.

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Citations

Dec 18, 2013·Annales de pathologie·Béma CoulibalyFrançois Labrousse
Sep 18, 2007·World Journal of Surgical Oncology·Ahmed AlzaraaNeha Dalal
Oct 2, 2007·Histopathology·F Campbell, B Azadeh
Apr 1, 2016·Nature Reviews. Clinical Oncology·Xavier M KeutgenElectron Kebebew
Apr 7, 2018·International Journal of Surgical Pathology·Ann Brinch Madelung, Sönke Detlefsen
Apr 26, 2014·World Journal of Radiology·Kousei IshigamiHiroshi Honda
Jun 13, 2012·Internal Medicine·Noritoshi KobayashiKensuke Kubota
Nov 2, 2017·The Indian Journal of Surgery·Mallika TewariH S Shukla
Sep 24, 2009·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Min-Shu HsiehChia-Tung Shun

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