Three cyclooctapeptides and one glycoside from Microtoena prainiana

Journal of Natural Products
Chong-Qian LiGuo-Lin Zhang

Abstract

Three new cyclic octapeptides, microtoenins A-C (1-3), and a new glycoside, 3'''-O-methylcrenatoside (4), along with several known compounds, were isolated from the ethanolic extract of the stems of Microtoena prainiana. Their structures were determined by spectral and chemical evidence. At a concentration of 0.01 mg/mL, 3'''-O-methylcrenatoside (4), crenatoside (5), and isocrenatoside (6) inhibited angiotensin converting enzyme (ACE) activity by more than 30%.

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Citations

Jun 10, 2010·Applied Microbiology and Biotechnology·Jack H WongF Liu
May 30, 2006·European Journal of Medicinal Chemistry·K LohithS Divakar
Jul 3, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Yibing WangChen Wang
Mar 9, 2006·Chemical Reviews·Ning-Hua Tan, Jun Zhou

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