Three Decades of Follow-up of Adults After Recovery From Invasive Pneumococcal Pneumonia

The American Journal of the Medical Sciences
Oluwadamilare O AjayiMaurice A Mufson

Abstract

Streptococcus pneumoniae infection is the most common cause of community-acquired pneumonia in adults. Invasive pneumococcal disease (IPD) carries a high case fatality rate. We investigated the lifespan of adults who recovered from IPD during a 32-year follow-up. We determined whether adults discharged after an episode of IPD from hospitals affiliated with the Marshall University Joan C. Edwards School of Medicine in Huntington, West Virginia from 1983-2003 were alive on June 30, 2014. Lifespan was assessed by Kaplan-Meier methodology, Cox proportional hazards multivariate analysis, life expectancy using life tables for West Virginia, years of potential life lost and serotype occurrence. The study group comprised 155 adults who survived IPD. They had a mean age at discharge of 64.6 years, mean lifespan after IPD of 7.1 years, mean expected lifespan after IPD of 17.0 years, mean age at death of 71.6 years and a mean life expectancy of 81.6 years. Only 14 (9.0%) patients lived longer than their life expectancy. Of the 13 comorbid diseases analyzed, cancer and neurologic diseases and the number of comorbid diseases suffered by each patient were the significant variables associated with survival. The mean years of potential life lo...Continue Reading

Citations

Dec 7, 2018·Expert Review of Respiratory Medicine·Charles Feldman, Erica Shaddock
Apr 12, 2018·International Journal of Molecular Sciences·Ronald AndersonCharles Feldman
Sep 9, 2019·The Lancet Infectious Diseases·Hugues Fausther-Bovendo, Gary Kobinger

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