Three-dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments

Optics Express
Yoshiaki YasunoToyohiko Yatagai


A two- and three-dimensional swept source optical coherence tomography (SS-OCT) system, which uses a ready-to-ship scanning light source, is demonstrated. The light source has a center wavelength of 1.31 mum, -3 dB wavelength range of 110 nm, scanning rate of 20 KHz, and high linearity in frequency scanning. This paper presents a simple calibration method using a fringe analysis technique for spectral rescaling. This SS-OCT system is capable of realtime display of two-dimensional OCT and can obtain three-dimensional OCT with a measurement time of 2 s. In vivo human anterior eye segments are investigated two- and three-dimensionally. The system sensitivity is experimentally determined to be 114 dB. The three-dimensional OCT volumes reveal the structures of the anterior eye segments, which are difficult to observe in two-dimensional OCT images.


Nov 22, 1991·Science·David HuangC A Puliafito
Aug 15, 2002·Journal of Biomedical Optics·Maciej WojtkowskiAdolf Friedrich Fercher
Sep 30, 2003·Optics Letters·Maciej WojtkowskiAndrzej Kowalczyk
Sep 24, 2005·Journal of Biomedical Optics·Michael ChomaJoseph A Izatt
Jan 18, 2006·Journal of Biomedical Optics·Anjul M DavisJoseph A Izatt
Nov 21, 2007·Optics Letters·Maciej WojtkowskiAdolf Friedrich Fercher
Nov 23, 2007·Optics Letters·B PovazayE Scherzer
Dec 13, 2007·Optics Letters·W DrexlerJames G Fujimoto
Mar 1, 1997·Optics Letters·S R ChinnJames G Fujimoto
Apr 21, 2003·Optics Express·R A LeitgebAdolf Friedrich Fercher
Nov 3, 2003·Optics Express·S H YunBrett E Bouma
May 17, 2004·Optics Express·R A LeitgebAdolf Friedrich Fercher
Nov 29, 2004·Optics Express·Jun ZhangZhongping Chen
Jan 24, 2005·Optics Express·Erich GötzingerChristoph K Hitzenberger
Jul 11, 2005·Optics Express·Benjamin J VakocBrett E Bouma
Jan 1, 1998·Journal of Biomedical Optics·G Ha Usler, M W Lindner


Aug 21, 2010·Eye & Contact Lens·Naoyuki Maeda
Sep 18, 2007·Journal of Biomedical Optics·Masahiro AkibaKin Pui Chan
Nov 13, 2007·Journal of Biomedical Optics·Adam M ZyskStephen A Boppart
Jan 1, 2008·Journal of Biomedical Optics·Masahiro Akiba, Kin Pui Chan
Nov 22, 2008·Journal of Biomedical Optics·Meng-Tsan TsaiChun-Ping Chiang
Mar 5, 2009·Journal of Biomedical Optics·Masato OhmiMasamitsu Haruna
Jan 5, 2011·Journal of Biomedical Optics·Yoshiaki YasunoTetsuro Oshika
Nov 28, 2012·Japanese Journal of Ophthalmology·Nobuyuki SatohHiroyuki Furukawa
Jun 7, 2013·Japanese Journal of Ophthalmology·Shizuka KohKohji Nishida
Apr 11, 2012·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Lindsey S FolioJoel S Schuman
May 11, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tetsuya AgawaYoshiaki Yasuno
Nov 12, 2013·Current Eye Research·Yong SunChuanqing Zhou
Jan 16, 2013·American Journal of Ophthalmology·Reina FukudaShiro Amano
Nov 28, 2012·Dental Materials : Official Publication of the Academy of Dental Materials·Amir NazariYasunori Sumi
Sep 11, 2012·Ophthalmology·Anna S MajanderKari Krootila
Jan 21, 2012·Journal of Cataract and Refractive Surgery·Eszter SzalaiLászló Módis
May 12, 2010·Journal of Cataract and Refractive Surgery·Yan LiDavid Huang
Dec 26, 2015·Journal of Cataract and Refractive Surgery·Akeno TamaokiKazuo Ichikawa
Dec 8, 2010·Zeitschrift für medizinische Physik·Adolf Friedrich Fercher
May 5, 2009·Ophthalmology·Shinichi FukudaTetsuro Oshika
Dec 2, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Meixiao ShenJianhua Wang
Apr 26, 2014·Journal of Refractive Surgery·Yuta UenoTetsuro Oshika
Nov 26, 2009·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Masahiro MiuraYoshiaki Yasuno
Dec 4, 2015·Indian Journal of Ophthalmology·Mukesh KumarDebarun Dutta
Oct 4, 2007·Acta Ophthalmologica Scandinavica·Keisuke KawanaTetsuro Oshika
Apr 29, 2014·IEEE Journal of Selected Topics in Quantum Electronics : a Publication of the IEEE Lasers and Electro-optics Society·Xiang LiZhongping Chen
Mar 15, 2015·Ophthalmology·Yuta UenoTetsuro Oshika
Nov 21, 2012·Seminars in Ophthalmology·Ernesto Golez, Mark Latina
Jul 26, 2014·Computers in Biology and Medicine·Robert KoprowskiZygmunt Wróbel
Dec 25, 2006·Optics Express·Hyungsik LimJohannes F de Boer
Mar 9, 2017·Biomedical Optics Express·René M WerkmeisterLeopold Schmetterer
Mar 9, 2017·Biomedical Optics Express·Thomas Klein, Robert Huber
Oct 7, 2017·The British Journal of Ophthalmology·Tommy C Y ChanVishal Jhanji
Jan 19, 2011·Eye·C K-S Leung, R N Weinreb
Jun 12, 2018·Journal of Refractive Surgery·Jeferson LautertMarianne O Price
Jul 21, 2017·Journal of Biomedical Optics·Wendy-Julie MadoreNicolas Godbout
Sep 26, 2017·Eye & Contact Lens·Rajini PegudaHelen Swarbrick
Dec 10, 2009·Optics Express·Tsung-Han TsaiJames G Fujimoto
Mar 23, 2010·Expert Review of Ophthalmology·Roxana Ursea, Ronald H Silverman
Mar 11, 2010·Expert Review of Anticancer Therapy·Michael DeCoro, Petra Wilder-Smith
Nov 18, 2014·Biomedical Optics Express·Wolfgang WieserRobert Huber
Feb 11, 2020·Japanese Journal of Ophthalmology·Sou MinamiHiroko Terasaki
Jun 10, 2009·Optics Express·Benjamin R BiedermannRobert Huber
Jul 24, 2015·Biomedical Optics Express·Christian Jirauschek, Robert Huber
Jun 12, 2008·Optics Express·Christoph M EigenwilligRobert Huber
Apr 3, 2009·Applied Optics·Changho ChongTooru Sakai
Mar 19, 2009·Optics Express·Ireneusz GrulkowskiMaciej Wojtkowski
Aug 21, 2006·Optics Express·Shuichi MakitaYoshiaki Yasuno
Dec 18, 2012·Biomedical Optics Express·Al-Hafeez DhallaJoseph A Izatt
Oct 20, 2012·Biomedical Optics Express·Wolfgang WieserRobert Huber
Jun 16, 2015·Optics Express·Adrian BraduAdrian Podoleanu
Mar 18, 2015·Biomedical Optics Express·Masahiro YamanariToru Nakazawa
Feb 3, 2016·Optics Express·Simon SchneiderChristian Koos
Feb 26, 2016·Optics Express·Sylvain RivetAdrian Podoleanu
Sep 7, 2018·Optics Express·Christoph K Hitzenberger
Jan 31, 2019·Optics Express·Yuye LingChristine P Hendon
Dec 19, 2019·Frontiers in Bioengineering and Biotechnology·Xinhan CuiJiaxu Hong
Sep 30, 2015·Biomedical Optics Express·Adrian BraduAdrian Podoleanu
Jul 1, 2017·Biomedical Optics Express·Yiwei ChenYoshiaki Yasuno
Jun 24, 2011·Biomedical Optics Express·Bernhard BaumannJames G Fujimoto
May 28, 2016·Biomedical Optics Express·Hideyuki WatanabeManabu Tanifuji
Dec 30, 2015·Biomedical Optics Express·Satoshi SugiyamaYoshiaki Yasuno
Mar 20, 2018·Biomedical Optics Express·Viacheslav MazlinA Claude Boccara
May 3, 2018·Optics Express·Néstor Uribe-PatarroyoBrett E Bouma
Jan 25, 2011·Biomedical Optics Express·Hiroyuki FurukawaKimiya Shimizu
May 15, 2006·Optics Express·Edward C LeeSeok H Yun
Mar 20, 2018·Biomedical Optics Express·Hyung-Jin KimBeop-Min Kim
Jan 24, 2018·Journal of Neurophysiology·Yu NakamichiManabu Tanifuji
May 16, 2018·Biomedical Optics Express·Myeong Jin JuYifan Jian
Feb 4, 2014·Optics Letters·Adrian Bradu, Adrian Podoleanu
Feb 19, 2019·Biomedical Optics Express·Ryan P McNabbAnthony N Kuo
Feb 1, 2021·Vision Research·Gaku KiuchiTetsuro Oshika
Jan 1, 2021·Optics Express·Okan AtalarKieran Parsons
Apr 4, 2021·Journal of Clinical Medicine·Michał DembskiEdward Wylęgała
Apr 21, 2021·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Kin WanPauline Cho

Related Concepts

Anterior Eyeball Segment Structure
Diagnostic Techniques, Surgical
Radiography, Dual-Energy Scanned Projection
Tomography, Optical Coherence
In Vivo

Related Feeds


Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

Cell Imaging in CNS

Here is the latest research on cell imaging and imaging modalities, including light-sheet microscopy, in the central nervous system.